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Ph.D. Thesis

Ali, Ataurehman (2022):
Analyzing the engineering potential of subtilosin A by probing the substrate promiscuity of the thioether forming sactisynthase AlbA. (Publisher's Version)
Darmstadt, Technische Universität Darmstadt,
DOI: 10.26083/tuprints-00021802,
[Ph.D. Thesis]

Anderl, Anita (2020):
Charakterisierung von Zellwandproteinen des Transglutaminase-Produzenten Streptomyces mobaraensis.
Darmstadt, Technische Universität,
DOI: 10.25534/tuprints-00011585,
[Ph.D. Thesis]

Bauch, Caroline D. (2013):
Development and validation of animal-free test methods to predict the skin sensitizing potential of chemicals.
Darmstadt, Technische Universität,
[Ph.D. Thesis]

Bauder, Michael (2022):
Design and Synthesis of macrocyclic FKBP51 ligands. (Publisher's Version)
Darmstadt, Technische Universität Darmstadt,
DOI: 10.26083/tuprints-00018565,
[Ph.D. Thesis]

Becker, Bastian (2021):
Peptide-conjugated dextran hybrids: Generation of a versatile module for cytosolic delivery of biomolecular cargoes. (Publisher's Version)
Darmstadt, Technische Universität Darmstadt,
DOI: 10.26083/tuprints-00019789,
[Ph.D. Thesis]

Bogen, Jan Patrick (2021):
Oligospecific Human Antibodies with Therapeutic Potential Derived from Immunized Chickens. (Publisher's Version)
Darmstadt, Technische Universität,
DOI: 10.26083/tuprints-00019360,
[Ph.D. Thesis]

Bohländer, Fabian (2021):
The immunomodulatory properties of the IgM- and IgA-enriched immunoglobulin preparation trimodulin. (Publisher's Version)
Darmstadt, Technische Universität,
DOI: 10.26083/tuprints-00019101,
[Ph.D. Thesis]

Boltz, Achim (2011):
Bi-specific Aptamers mediating Tumour Cell Lysis.
Darmstadt, Technische Universität,
[Ph.D. Thesis]

Brahm, Kevin (2020):
Untersuchung von Peptidomimetika als Inhibitoren für das Chemokin CXCL8.
Darmstadt, Technische Universität,
DOI: 10.25534/tuprints-00011794,
[Ph.D. Thesis]

Capito, Florian (2014):
Development and monitoring of a novel monoclonal antibody purification strategy.
Darmstadt, Technische Universität,
[Ph.D. Thesis]

Carrara, Stefania C. (2023):
Generation of Multispecific Antibodies with Immune Cell Modulating Functions. (Publisher's Version)
Darmstadt, Technische Universität Darmstadt,
DOI: 10.26083/tuprints-00023023,
[Ph.D. Thesis]

Cavlovic, Lidija (2015):
Wirkung von ionisierender Strahlung auf Proteom und Lipidom sowie auf zelluläre und mitochondriale Aktivität.
Darmstadt, Technische Universität,
[Ph.D. Thesis]

Decker, Victoria (2016):
Beeinflussung von Zellphysiologie und mitochondrialer Funktion durch Alzheimer Demenz-assoziiertes Amyloides-β Peptid.
Darmstadt, Technische Universität Darmstadt,
[Ph.D. Thesis]

Djemal, Leila (2022):
Variability and viral safety of cell culture media to ensure process performance in the biopharmaceutical industry. (Publisher's Version)
Darmstadt, Technische Universität,
DOI: 10.26083/tuprints-00020993,
[Ph.D. Thesis]

Džinić, Tamara (2017):
Interplay of ionizing radiation, oxygen, ROS and age-associated diseases.
Darmstadt, Technische Universität,
[Ph.D. Thesis]

Ebenig, Aileen (2019):
Biopolymeric scaffold to achieve high drug-to-antibody ratios using site specific conjugation strategies.
Darmstadt, Technische Universität,
[Ph.D. Thesis]

Elter, Adrian Elias Curd (2021):
Chicken-derived antibodies for therapeutic, diagnostic and bioprocessing applications. (Publisher's Version)
Darmstadt, Technische Universität Darmstadt,
DOI: 10.26083/tuprints-00019728,
[Ph.D. Thesis]

Empting, Martin (2013):
Disubstituted 1,2,3-Triazoles: A Multitool for Biomolecular Chemistry.
Darmstadt, Technische Universität,
[Ph.D. Thesis]

Fabritz, Sebastian (2013):
Bioconjugation of Peptides on Cube-octameric Silsesquioxanes.
Darmstadt, Technische Universität,
[Ph.D. Thesis]

Fiebig, David Alexander (2019):
Das Dispaseautolyse-induzierende Protein von Streptomyces mobaraensis. Struktur, Katalysemechanismus und Glutaminbindestellen für die Modifikation durch mikrobielle Transglutaminase.
Darmstadt, Technische Universität,
[Ph.D. Thesis]

Fittler, Heiko (2015):
Peptidic inhibitors of therapeutically relevant proteases: Design, synthesis, and functional evaluation.
Darmstadt, Technische Universität,
[Ph.D. Thesis]

Frenzel, Monika (2012):
Mitochondrial ageing in rat brain areas and human fibroblasts.
Darmstadt, Technische Universität,
[Ph.D. Thesis]

Glotzbach, Bernhard (2013):
Isolierung und Charakterisierung hochaffiner Cystinknoten- basierter Matriptase-1 Inhibitoren.
Darmstadt, Technische Universität,
[Ph.D. Thesis]

Haehle, Andreas (2020):
Elucidation of the molecular and cellular mechanisms of FKBP51-selective inhibitors.
Darmstadt, Technische Universität,
DOI: 10.25534/tuprints-00013235,
[Ph.D. Thesis]

Heidrich, Nicolas Georges (2011):
Superkomplexe aus Algen und Cyanobakterien - Isolierung, Charakterisierung und strukturelle Untersuchung.
Technische Universität,
[Ph.D. Thesis]

Heil, Stefanie (2012):
Evolutive Optimierung mikrobieller Lipasen und Esterasen in Hinblick auf Substratspezifität und Enantioselektivität.
Darmstadt, Technische Universität,
[Ph.D. Thesis]

Heymann, Tim (2023):
Synthesis and mass spectrometry based characterization of chemical tools to explore FK506 binding proteins. (Publisher's Version)
Darmstadt, Technische Universität Darmstadt,
DOI: 10.26083/tuprints-00021441,
[Ph.D. Thesis]

Hinz, Steffen (2021):
Tailor-made antibodies by multidimensional functional screening. (Publisher's Version)
Darmstadt, Technische Universität,
DOI: 10.26083/tuprints-00014598,
[Ph.D. Thesis]

Hofmann, Monika (2014):
Influence of the Maillard reaction on the allergenicity of food allergens.
Darmstadt, Technische Universität,
[Ph.D. Thesis]

Hofmann, Tim Lothar (2020):
Intein mediated high throughput screening for bispecific antibodies. (Publisher's Version)
Darmstadt, Technische Universität,
DOI: 10.25534/tuprints-00013280,
[Ph.D. Thesis]

Hofmeyer, Thomas (2013):
Über die Charakterisierung und funktionelle Produktion der Oligomerisierungsdomäne des humanen C4b-Bindeproteins.
In: Dissertation, Darmstadt, TU Darmstadt, Technische Universität,
[Ph.D. Thesis]

Husslik, Felix (2016):
Analysis of the IgE epitope profile of the soybean allergen Gly m 4.
Darmstadt, Technische Universität Darmstadt,
[Ph.D. Thesis]

Hörner, Sebastian (2017):
Biofunctionalization of Silsesquioxane Nanoparticles.
Darmstadt, Technische Universität,
[Ph.D. Thesis]

Jäger, Sebastian Michael (2022):
Fc Antigen-Binding Fragment Drug Conjugates as Novel Antibody-Based Format for Targeted Drug Delivery. (Publisher's Version)
Darmstadt, Technische Universität Darmstadt,
DOI: 10.26083/tuprints-00020360,
[Ph.D. Thesis]

Jöst, Marina (2016):
Etablierung von zellbasierten Assays zur Identifizierung von Inhibitoren des Chemokins CXCL8.
Technische Universität Darmstadt, Clemens-Schöpf-Institut für Organische Chemie und Biochemie,
[Ph.D. Thesis]

Kaempffe, Anna (2022):
Evaluation of ADC Physicochemical Characteristics and Their Impact on Pharmacokinetics in Transgenic huFcRn Mice. (Publisher's Version)
Darmstadt, Technische Universität Darmstadt,
DOI: 10.26083/tuprints-00021848,
[Ph.D. Thesis]

Knaup, Fabian Henrik (2023):
Synthesis and investigation of 2-substituted hetero-/arylacetic acids as bottom groups for selective inhibitors of the FK506-binding protein 51 (FKBP51). (Publisher's Version)
Darmstadt, Technische Universität Darmstadt,
DOI: 10.26083/tuprints-00023707,
[Ph.D. Thesis]

Kolos, Jürgen (2023):
Synthesis of tailor-made bicyclic [4.3.1] aza-amides. (Publisher's Version)
Darmstadt, Technische Universität Darmstadt,
DOI: 10.26083/tuprints-00017571,
[Ph.D. Thesis]

Korbus, Michael (2015):
Entwicklung und Charakterisierung einer photoschaltbaren Histondeacetylase-ähnlichen Amidohydrolase.
Darmstadt, Technische Universität,
[Ph.D. Thesis]

Kratochwil, Manuela (2016):
Effects of ageing, calorie restriction and ageing-associated diseases on the mitochondrial proteome.
Darmstadt, Technische Universität,
[Ph.D. Thesis]

Loggen, Franziska (2015):
Über die Etablierung neuartiger Verfahren zur DNA vermittelten in vitro Genotyp-Phänotyp-Kopplung.
Darmstadt, Technische Universität,
[Ph.D. Thesis]

Maaß, Franziska (2014):
Protein Engineering an Cystinknoten-Miniproteinen: Generierung von immunregulatorischen Varianten mit optimierten Bindungseigenschaften und Gerüststrukturen.
Darmstadt, Technische Universität,
[Ph.D. Thesis]

Mang, Tanja (2019):
Evaluation of the therapeutic potential of GDF5 mutants to treat osteoarthritis.
Darmstadt, Technische Universität,
[Ph.D. Thesis]

Mao, Tianqi (2020):
Development of Novel Small-Molecule Degraders of FK506-Binding Protein 51.
Darmstadt, Technische Universität,
DOI: 10.25534/tuprints-00011503,
[Ph.D. Thesis]

Merz, Stephanie Katharina (2022):
Development and Characterization of a FKBP51FK1 Affinity Matrix for Protein-Protein Interaction Studies. (Publisher's Version)
Darmstadt, Technische Universität Darmstadt,
DOI: 10.26083/tuprints-00022958,
[Ph.D. Thesis]

Meyners, Christian Stephan (2017):
Selectivity in histone deacetylase inhibition: A biophysical approach.
Darmstadt, Technische Universität,
[Ph.D. Thesis]

Mueller, Lena (2019):
Chemical synthesis of switchable peptide-based nanopores: from ion channels to bio-inspired materials.
Darmstadt, Technische Universität,
DOI: 10.25534/tuprints-00011495,
[Ph.D. Thesis]

Müller, Sandra Rita (2022):
Validation and characterization of monoclonal antibodies to target cancer stem cells and to develop new anti-cancer therapies. (Publisher's Version)
Darmstadt, Technische Universität Darmstadt,
DOI: 10.26083/tuprints-00021677,
[Ph.D. Thesis]

Nasu, Daichi (2016):
Non-Natural Elements for Peptide-Based Molecular Design, Structural Analysis, and Functional Modifications.
Darmstadt, Technische Universität Darmstadt,
[Ph.D. Thesis]

Pekar, Lukas (2021):
Novel technologies for antibody hit discovery and engineering of antibody-like proteins with therapeutic relevance. (Publisher's Version)
Darmstadt, Technische Universität,
DOI: 10.26083/tuprints-00017513,
[Ph.D. Thesis]

Pirzer, Thomas (2018):
Generation of anti-HER1/2 immunotoxins by protein ligation using split inteins.
Darmstadt, Technische Universität,
[Ph.D. Thesis]

Rieker, Marcel (2020):
Targeted Combination Therapy: Discovery and Evaluation of Synergistic Anticancer Effects of Anti-HER2-Duocarmycin Antibody-Drug Conjugates Combined with ATR Inhibitors.
Darmstadt, Shaker Verlag GmbH, Technische Universität, ISBN 978-3-8440-6478-0,
DOI: 10.25534/tuprints-00008615,
[Ph.D. Thesis]

Rink, Ina (2016):
Untersuchungsmethoden für die chemokininduzierte Migration von Leukozyten.
Darmstadt, Technische Universität Darmstadt,
[Ph.D. Thesis]

Roßkopf, Janis Mario (2019):
Improved Drug Delivery of next-generation Antibody-Drug Conjugates by utilizing tumor-associated proteases.
Darmstadt, Technische Universität,
DOI: 10.25534/tuprints-00009685,
[Ph.D. Thesis]

Rutkowski, Emilia (2019):
Erstcharakterisierung des C‐Typ Lektin‐ähnlichen Glykoproteins Clr‐a.
Darmstadt, Technische Universität,
[Ph.D. Thesis]

Sapir, Ashi (2020):
Evaluation of Yeast Display Fab Libraries Derived from Tumor Infiltrating B Cells.
Darmstadt, Technische Universität,
DOI: 10.25534/tuprints-00011371,
[Ph.D. Thesis]

Schirmer, Matthias (2017):
Erschließung einer natürlichen Peptid-Protein-Wechselwirkung als molekulare Grundstruktur zur hochaffinen Kopplung von Proteinen und Entwicklung biotechnologischer Anwendungsmodule.
Darmstadt, Technische Universität,
[Ph.D. Thesis]

Schmidt, Carolin (2020):
Functional characterization of a new IgM- and IgA-enriched immunoglobulin preparation. (Publisher's Version)
Darmstadt, Technische Universität,
DOI: 10.25534/tuprints-00015398,
[Ph.D. Thesis]

Schneider, Hendrik Peter Günter (2020):
Multivalent Functionalized Dextran-Antibody Conjugates for Efficient Tumor Cell Killing.
Darmstadt, Technische Universität,
DOI: 10.25534/tuprints-00011502,
[Ph.D. Thesis]

Schnellbächer, Mark (2017):
Kinetische und präparative Studien mit neuen Sialinsäuresynthasen aus Neisseria meningitidis und Campylobacter jejuni.
Darmstadt, Technische Universität,
[Ph.D. Thesis]

Schwaßmann, Helena J. (2010):
Analyse von Atmungskettenkomplexen aus Organellen von Chlamydomonas reinhardtii und Rattus norvegicus.
Darmstadt, Technische Universität,
[Ph.D. Thesis]

Schäfer, Eva Regine (2012):
Massenspektrometrische und gelelektrophoretische Analyse altersabhängiger Veränderungen des mitochondrialen Proteoms von Modellorganismen.
Darmstadt, Technische Universität,
[Ph.D. Thesis]

Sellmann, Carolin (2016):
Balancing Efficacy and Selectivity of Bispecific c-METxEGFR Antibodies.
Darmstadt, Technische Universität Darmstadt,
[Ph.D. Thesis]

Steinhäuser, Kerstin (2017):
Funktion und Regulation des neuen Tubulin-assoziierten Proteins RITA.
Darmstadt, Technische Universität,
[Ph.D. Thesis]

Thilmany, Sandra Cornelia (2013):
Das mitochondriale Proteom von Rattus norvegicus in Abhängigkeit von Alter und Kalorienrestriktion.
Darmstadt, Technische Universität,
[Ph.D. Thesis]

Tomaszowski, Michael (2013):
Neue Miniproteininhibitoren gegen die humane Typ II Transmembranserinprotease Matriptase (MT-SPI).
Darmstadt, Technische Universität,
[Ph.D. Thesis]

Uth, Christina (2016):
Development of bioorthogonal synthetic strategies towards hybrid macromolecular conjugates with tailored properties.
Darmstadt, Technische Universität,
[Ph.D. Thesis]

Valldorf, Bernhard (2016):
Multivalent display of functional biomacromolecules: a modular approach.
Darmstadt, Technische Universität Darmstadt,
[Ph.D. Thesis]

Voll, Andreas Markus (2023):
Design, synthesis and biological evaluation of novel FKBP51 ligands. (Publisher's Version)
Darmstadt, Technische Universität Darmstadt,
DOI: 10.26083/tuprints-00017949,
[Ph.D. Thesis]

Weber, Niklas (2017):
Structure-Based Monomerization of Human Serine Protease HTRA1 towards Evolutive Engineering of Activity Modulators.
Darmstadt, Technische Universität,
[Ph.D. Thesis]

Weiß, Christine Hilde (2022):
Impact of iron on CHO metabolism and recombinant protein production. (Publisher's Version)
Darmstadt, Technische Universität,
DOI: 10.26083/tuprints-00021046,
[Ph.D. Thesis]

Winterling, Karina (2018):
Immunogenic Determinants of Coagulation Factor VIII.
Darmstadt, Technische Universität,
[Ph.D. Thesis]

Wohlmann, Andreas (2014):
Signaltransduktion, spezifische Hemmung und biotechnologische Anwendung des humanen TSLP-Rezeptors.
Darmstadt, Technische Universität,
[Ph.D. Thesis]

Yanakieva, Desislava (2020):
Ultra-High-Throughput Single-Cell Functional Screening by Combination of Microfluidics and GMD-FACS.
Darmstadt, Technische Universität,
DOI: 10.25534/tuprints-00013464,
[Ph.D. Thesis]

Zielonka, Stefan (2015):
The shark strikes twice: Generation of Mono- and Bispecific High-Affinity vNAR Antibody Domains via Step-Wise Affinity Maturation.
Darmstadt, Technische Universität,
[Ph.D. Thesis]

Zimmermann, Martina (2021):
The impact of S-sulfocysteine in cell culture media. (Publisher's Version)
Darmstadt, Technische Universität,
DOI: 10.26083/tuprints-00014299,
[Ph.D. Thesis]

Zindel, Stephan (2013):
Struktur und Funktion enzymatisch vernetzbarer Proteaseinhibitoren von Streptomyces mobaraensis.
Darmstadt, Technische Universität,
[Ph.D. Thesis]

Data

Bogen, Jan Patrick ; Carrara, Stefania Candela ; Fiebig, David ; Grzeschik, Julius ; Hock, Björn ; Kolmar, Harald (2023):
Supplemental Information with antibody sequences. (Publisher's Version)
Darmstadt, Universitäts- und Landesbibliothek Darmstadt,
DOI: 10.26083/tuprints-00017895,
[Data]