2025

Schoenfeld, Katrin ; Harwardt, Julia ; Kolmar, Harald (2025)
Better safe than sorry: dual targeting antibodies for cancer immunotherapy.
In: Biological Chemistry, 2024
doi: 10.26083/tuprints-00027608
Article, Secondary publication, Publisher's Version

2024

Arras, Paul ; Zimmermann, Jasmin ; Lipinski, Britta ; Valldorf, Bernhard ; Evers, Andreas ; Elter, Desislava ; Krah, Simon ; Doerner, Achim ; Guarnera, Enrico ; Siegmund, Vanessa ; Kolmar, Harald ; Pekar, Lukas ; Zielonka, Stefan (2024)
Bovine ultralong CDR-H3 derived knob paratopes elicit potent TNF-α neutralization and enable the generation of novel adalimumab-based antibody architectures with augmented features.
In: Biological Chemistry, 2024
doi: 10.26083/tuprints-00027605
Article, Secondary publication, Publisher's Version

Becker, Bastian ; Englert, Simon ; Schneider, Hendrik ; Yanakieva, Desislava ; Hofmann, Sarah ; Dombrowsky, Carolin ; Macarrón Palacios, Arturo ; Bitsch, Sebastian ; Elter, Adrian ; Meckel, Tobias ; Kugler, Benedikt ; Schirmacher, Anastasyia ; Avrutina, Olga ; Diederichsen, Ulf ; Kolmar, Harald (2024)
Multivalent dextran hybrids for efficient cytosolic delivery of biomolecular cargoes.
In: Journal of Peptide Science : the official Journal of the European Peptide Society, 2021, 27 (4)
doi: 10.26083/tuprints-00017809
Article, Secondary publication, Publisher's Version

Bischoff, Matthias ; Mayer, Peter ; Meyners, Christian ; Hausch, Felix (2024)
Enantioselective Synthesis of a Tricyclic, sp³‐Rich Diazatetradecanedione: an Amino Acid‐Based Natural Product‐Like Scaffold.
In: Chemistry – A European Journal, 2020, 26 (21)
doi: 10.26083/tuprints-00015975
Article, Secondary publication, Publisher's Version

Bitsch, Peter ; Baum, Eva S. ; Beltrán Hernández, Irati ; Bitsch, Sebastian Harald ; Harwood, Jakob ; Oliveira, Sabrina ; Kolmar, Harald (2024)
Penetration of Nanobody-Dextran Polymer Conjugates through Tumor Spheroids.
In: Pharmaceutics, 2023, 15 (10)
doi: 10.26083/tuprints-00024648
Article, Secondary publication, Publisher's Version

Bogen, Jan P. ; Hinz, Steffen C. ; Grzeschik, Julius ; Ebenig, Aileen ; Krah, Simon ; Zielonka, Stefan ; Kolmar, Harald (2024)
Dual Function pH Responsive Bispecific Antibodies for Tumor Targeting and Antigen Depletion in Plasma.
In: Frontiers in Immunology, 2019, 10
doi: 10.26083/tuprints-00015735
Article, Secondary publication, Publisher's Version

Bogen, Jan P. ; Storka, Juliana ; Yanakieva, Desislava ; Fiebig, David ; Grzeschik, Julius ; Hock, Björn ; Kolmar, Harald (2024)
Isolation of Common Light Chain Antibodies from Immunized Chickens Using Yeast Biopanning and Fluorescence‐Activated Cell Sorting.
In: Biotechnology Journal : Systems and Synthetic Biology, Nanobiotech, Medicine, 2020, 16 (3)
doi: 10.26083/tuprints-00017449
Article, Secondary publication, Publisher's Version

Böhm, Alexander ; Trosien, Simon ; Avrutina, Olga ; Kolmar, Harald ; Biesalski, Markus (2024)
Covalent Attachment of Enzymes to Paper Fibers for Paper-Based Analytical Devices.
In: Frontiers in Chemistry, 2018, 6
doi: 10.26083/tuprints-00015860
Article, Secondary publication, Publisher's Version

Carrara, Stefania C. ; Bogen, Jan P. ; Fiebig, David ; Grzeschik, Julius ; Hock, Björn ; Kolmar, Harald (2024)
Targeted Phagocytosis Induction for Cancer Immunotherapy via Bispecific MerTK-Engaging Antibodies.
In: International Journal of Molecular Sciences, 2022, 23 (24)
doi: 10.26083/tuprints-00027673
Article, Secondary publication, Publisher's Version

Carrara, Stefania C. ; Fiebig, David ; Bogen, Jan P. ; Grzeschik, Julius ; Hock, Björn ; Kolmar, Harald (2024)
Recombinant Antibody Production Using a Dual-Promoter Single Plasmid System.
In: Antibodies, 2021, 10 (2)
doi: 10.26083/tuprints-00019564
Article, Secondary publication, Publisher's Version

Cohen, Benjamin (2024)
Macrophages Cell Surface Proteome Analysis for Identification of Markers and Therapeutic Targets.
Technische Universität Darmstadt
doi: 10.26083/tuprints-00028840
Ph.D. Thesis, Primary publication, Publisher's Version

Deutscher, Robin C. E. ; Karagöz, Mustafa Safa ; Purder, Patrick L. ; Kolos, Jürgen M. ; Meyners, Christian ; Oki Sugiarto, Wisely ; Krajczy, Patryk ; Tebbe, Frederike ; Geiger, Thomas M. ; Ünal, Can ; Hellmich, Ute A. ; Steinert, Michael ; Hausch, Felix (2024)
[4.3.1]Bicyclic FKBP Ligands Inhibit Legionella Pneumophila Infection by LpMip‐Dependent and LpMip‐Independent Mechanisms.
In: ChemBioChem, 2023, 24 (21)
doi: 10.26083/tuprints-00027244
Article, Secondary publication, Publisher's Version

Djemal, Leila ; Fournier, Clemence ; Hagen, Joerg von ; Kolmar, Harald ; Deparis, Véronique (2024)
Review: High temperature short time treatment of cell culture media and feed solutions to mitigate adventitious viral contamination in the biopharmaceutical industry.
In: Biotechnology Progress, 2021, 37 (3)
doi: 10.26083/tuprints-00027676
Article, Secondary publication, Publisher's Version

Djemal, Leïla ; Hagen, Joerg von ; Kolmar, Harald ; Deparis, Véronique (2024)
Characterization of soy protein hydrolysates and influence of its iron content on monoclonal antibody production by a murine hybridoma cell line.
In: Biotechnology Progress, 2021, 37 (4)
doi: 10.26083/tuprints-00021528
Article, Secondary publication, Publisher's Version

Eckes, Stefanie (2024)
Modifikation von Proteinen mittels Photosensibilisatoren für die strukturierte Proteinimmobilisierung und Quervernetzung von Biomaterialien.
Technische Universität Darmstadt
doi: 10.26083/tuprints-00026689
Ph.D. Thesis, Primary publication, Publisher's Version

Elter, Adrian ; Bogen, Jan P. ; Habermann, Jan ; Kolmar, Harald (2024)
Vom Huhn abgeleitete Antikörper für Diagnostik und Immuntherapie.
In: BIOspektrum : Das Magazin für Biowissenschaften, 2021, 27 (5)
doi: 10.26083/tuprints-00023545
Article, Secondary publication, Publisher's Version

Elter, Adrian ; Bogen, Jan P. ; Hinz, Steffen C. ; Fiebig, David ; Macarrón Palacios, Arturo ; Grzeschik, Julius ; Hock, Björn ; Kolmar, Harald (2024)
Humanization of Chicken‐Derived scFv Using Yeast Surface Display and NGS Data Mining.
In: Biotechnology Journal : Systems & Synthetic Biology, Nanobiotech, Medicine, 2021, 16 (3)
doi: 10.26083/tuprints-00017792
Article, Secondary publication, Publisher's Version

Geiger, Thomas M. ; Walz, Michael ; Meyners, Christian ; Kuehn, Angela ; Dreizler, Johannes K. ; Sugiarto, Wisely O. ; Maciel, Edvaldo V. S. ; Zheng, Min ; Lermyte, Frederik ; Hausch, Felix (2024)
Discovery of a Potent Proteolysis Targeting Chimera Enables Targeting the Scaffolding Functions of FK506‐Binding Protein 51 (FKBP51).
In: Angewandte Chemie International Edition, 2024, 63 (3)
doi: 10.26083/tuprints-00027257
Article, Secondary publication, Publisher's Version

Geiger, Thomas Maximilian (2024)
Targeted protein degradation of FK506-binding proteins.
Technische Universität Darmstadt
doi: 10.26083/tuprints-00026757
Ph.D. Thesis, Primary publication, Publisher's Version

Grotz, Melanie ; Gijzel, Lieke van ; Bitsch, Peter ; Carrara, Stefania C. ; Kolmar, Harald ; Garg, Sakshi (2024)
Mimicking the immunosuppressive impact of fibroblasts in a 3D multicellular spheroid model.
In: Frontiers in Drug Discovery, 2024, 4
doi: 10.26083/tuprints-00027873
Article, Secondary publication, Publisher's Version

Habeck, Tanja ; Maciel, Edvaldo Vasconcelos Soares ; Kretschmer, Kevin ; Lermyte, Frederik (2024)
Charge site manipulation to enhance top‐down fragmentation efficiency.
In: Proteomics : Proteomics and Systems Biology, 2024, 24 (3-4)
doi: 10.26083/tuprints-00027109
Article, Secondary publication, Publisher's Version

Habermann, Jan (2024)
Anti-idiotype antibodies for biomedical applications.
Technische Universität Darmstadt
doi: 10.26083/tuprints-00026540
Ph.D. Thesis, Primary publication, Publisher's Version

Hadjabdelhafid-Parisien, Adem ; Bitsch, Sebastian ; Macarrón Palacios, Arturo ; Deweid, Lukas ; Kolmar, Harald ; Pelletier, Joelle N. (2024)
Tag-free, specific conjugation of glycosylated IgG1 antibodies using microbial transglutaminase.
In: RSC Advances, 2022, 12 (52)
doi: 10.26083/tuprints-00027672
Article, Secondary publication, Publisher's Version

Harwardt, Julia (2024)
Merge Two into One: Multispecific Symmetric Antibodies for Cancer Immunotherapy.
Technische Universität Darmstadt
doi: 10.26083/tuprints-00027848
Ph.D. Thesis, Primary publication, Publisher's Version

Hofmann, Tim ; Schmidt, Johannes ; Ciesielski, Elke ; Becker, Stefan ; Rysiok, Thomas ; Schütte, Mark ; Toleikis, Lars ; Kolmar, Harald ; Doerner, Achim (2024)
Intein mediated high throughput screening for bispecific antibodies.
In: mAbs, 2020, 12 (1)
doi: 10.26083/tuprints-00027688
Article, Secondary publication, Publisher's Version

Hähle, Andreas ; Merz, Stephanie ; Meyners, Christian ; Hausch, Felix (2024)
The Many Faces of FKBP51.
In: Biomolecules, 2019, 9 (1)
doi: 10.26083/tuprints-00016874
Article, Secondary publication, Publisher's Version

Jagtap, Pravin Kumar Ankush ; Kubelka, Tomáš ; Soni, Komal ; Will, Cindy L. ; Garg, Divita ; Sippel, Claudia ; Kapp, Tobias G. ; Potukuchi, Harish Kumar ; Schorpp, Kenji ; Hadian, Kamyar ; Kessler, Horst ; Lührmann, Reinhard ; Hausch, Felix ; Bach, Thorsten ; Sattler, Michael (2024)
Identification of phenothiazine derivatives as UHM-binding inhibitors of early spliceosome assembly.
In: Nature Communications, 2020, 11 (1)
doi: 10.26083/tuprints-00023981
Article, Secondary publication, Publisher's Version

Jäger, Anita (2024)
Identification of novel antagonists against skin relevant molecular targets in mediation of itch and inflammation.
Technische Universität Darmstadt
doi: 10.26083/tuprints-00023314
Ph.D. Thesis, Primary publication, Publisher's Version

Jäger, Sebastian ; Dickgiesser, Stephan ; Tonillo, Jason ; Hecht, Stefan ; Kolmar, Harald ; Schröter, Christian (2024)
EGFR binding Fc domain-drug conjugates: stable and highly potent cytotoxic molecules mediate selective cell killing.
In: Biological Chemistry, 2022, 403 (5-6)
doi: 10.26083/tuprints-00027284
Article, Secondary publication, Publisher's Version

Krah, Simon ; Kolmar, Harald ; Becker, Stefan ; Zielonka, Stefan (2024)
Engineering IgG-Like Bispecific Antibodies — An Overview.
In: Antibodies, 2018, 7 (3)
doi: 10.26083/tuprints-00015758
Article, Secondary publication, Publisher's Version

Lerma Romero, Jorge Alberto (2024)
Modulation of the FKBP51 structure by protein engineering and isolation of conformation-locking antibodies and affibodies.
Technische Universität Darmstadt
doi: 10.26083/tuprints-00026563
Ph.D. Thesis, Primary publication, Publisher's Version

Lermyte, Frederik (2024)
The need for open and FAIR data in top‐down proteomics.
In: Proteomics : Proteomics and Systems Biology, 2024, 24 (3-4)
doi: 10.26083/tuprints-00027108
Article, Secondary publication, Publisher's Version

Macarrón Palacios, Arturo ; Grzeschik, Julius ; Deweid, Lukas ; Krah, Simon ; Zielonka, Stefan ; Rösner, Thies ; Peipp, Matthias ; Valerius, Thomas ; Kolmar, Harald (2024)
Specific Targeting of Lymphoma Cells Using Semisynthetic Anti-Idiotype Shark Antibodies.
In: Frontiers in Immunology, 2020, 11
doi: 10.26083/tuprints-00017467
Article, Secondary publication, Publisher's Version

Martinelli, Silvia ; Anderzhanova, Elmira A. ; Bajaj, Thomas ; Wiechmann, Svenja ; Dethloff, Frederik ; Weckmann, Katja ; Heinz, Daniel E. ; Ebert, Tim ; Hartmann, Jakob ; Geiger, Thomas M. ; Döngi, Michael ; Hafner, Kathrin ; Pöhlmann, Max L. ; Jollans, Lee ; Philipsen, Alexandra ; Schmidt, Susanne V. ; Schmidt, Ulrike ; Maccarrone, Giuseppina ; Stein, Valentin ; Hausch, Felix ; Turck, Christoph W. ; Schmidt, Mathias V. ; Gellner, Anne-Kathrin ; Kuster, Bernhard ; Gassen, Nils C. (2024)
Stress-primed secretory autophagy promotes extracellular BDNF maturation by enhancing MMP9 secretion.
In: Nature Communications, 2021, 12 (1)
doi: 10.26083/tuprints-00023586
Article, Secondary publication, Publisher's Version

Moisant, Rémy (2024)
Toward a robust lipid supplementation for SP2/0 fed-batch culture: Improving process performance by leveraging lipoprotein variability.
Technische Universität Darmstadt
doi: 10.26083/tuprints-00026549
Ph.D. Thesis, Primary publication, Publisher's Version

Mueller, Lena K. ; Baumruck, Andreas C. ; Zhdanova, Hanna ; Tietze, Alesia A. (2024)
Challenges and Perspectives in Chemical Synthesis of Highly Hydrophobic Peptides.
In: Frontiers in Bioengineering and Biotechnology, 2020, 8
doi: 10.26083/tuprints-00016102
Article, Secondary publication, Publisher's Version

Oliviero, Claudia ; Hinz, Steffen C. ; Bogen, Jan P. ; Kornmann, Henri ; Hock, Björn ; Kolmar, Harald ; Hagens, Gerrit (2024)
Generation of a host cell line containing a MAR-rich landing pad for site-specific integration and expression of transgenes.
In: Biotechnology Progress, 2022, 38 (4)
doi: 10.26083/tuprints-00027669
Article, Secondary publication, Publisher's Version

Pekar, Lukas ; Klewinghaus, Daniel ; Arras, Paul ; Carrara, Stefania C. ; Harwardt, Julia ; Krah, Simon ; Yanakieva, Desislava ; Toleikis, Lars ; Smider, Vaughn V. ; Kolmar, Harald ; Zielonka, Stefan (2024)
Milking the Cow: Cattle-Derived Chimeric Ultralong CDR-H3 Antibodies and Their Engineered CDR-H3-Only Knobbody Counterparts Targeting Epidermal Growth Factor Receptor Elicit Potent NK Cell-Mediated Cytotoxicity.
In: Frontiers in Immunology, 2021, 12
doi: 10.26083/tuprints-00019967
Article, Secondary publication, Publisher's Version

Pfeifer Serrahima, Jordi ; Schoenfeld, Katrin ; Kühnel, Ines ; Harwardt, Julia ; Macarrón Palacios, Arturo ; Prüfer, Maren ; Kolaric, Margareta ; Oberoi, Pranav ; Kolmar, Harald ; Wels, Winfried S. (2024)
Bispecific killer cell engagers employing species cross-reactive NKG2D binders redirect human and murine lymphocytes to ErbB2/HER2-positive malignancies.
In: Frontiers in Immunology, 2024, 15
doi: 10.26083/tuprints-00028083
Article, Secondary publication, Publisher's Version

Reinwarth, Michael ; Avrutina, Olga ; Fabritz, Sebastian ; Kolmar, Harald (2024)
Fragmentation follows structure: top-down mass spectrometry elucidates the topology of engineered cystine-knot miniproteins.
In: PLOS ONE, 2014, 9 (10)
doi: 10.26083/tuprints-00027627
Article, Secondary publication, Publisher's Version

Rhiel, Laura ; Krah, Simon ; Günther, Ralf ; Becker, Stefan ; Kolmar, Harald ; Hock, Björn (2024)
REAL-Select: Full-Length Antibody Display and Library Screening by Surface Capture on Yeast Cells.
In: PLOS ONE, 2014, 9 (12)
doi: 10.26083/tuprints-00027624
Article, Secondary publication, Publisher's Version

Schoenfeld, Katrin (2024)
Functionality-Enhanced Antibodies for Precision Cancer Therapy.
Technische Universität Darmstadt
doi: 10.26083/tuprints-00028569
Ph.D. Thesis, Primary publication, Publisher's Version

Schraut, Karla‐Gerlinde ; Kalnytska, Oleksandra ; Lamp, Daniel ; Jastroch, Martin ; Eder, Matthias ; Hausch, Felix ; Gassen, Nils C. ; Moore, Sarah ; Nagaraj, Nagarjuna ; Lopez, Juan P. ; Chen, Alon ; Schmidt, Mathias V. (2024)
Loss of the psychiatric risk factor SLC6A15 is associated with increased metabolic functions in primary hippocampal neurons.
In: European Journal of Neuroscience, 2020, 53 (2)
doi: 10.26083/tuprints-00016168
Article, Secondary publication, Publisher's Version

Schröter, Christian ; Becker, Jan ; Krah, Simon ; Zielonka, Stefan ; Doerner, Achim ; Rhiel, Laura ; Günther, Ralf ; Toleikis, Lars ; Kolmar, Harald ; Hock, Björn ; Becker, Stefan (2024)
Selection of Antibodies with Tailored Properties by Application of High-Throughput Multiparameter Fluorescence-Activated Cell Sorting of Yeast-Displayed Immune Libraries.
In: Molecular Biotechnology, 2018, 60
doi: 10.26083/tuprints-00027671
Article, Secondary publication, Publisher's Version

Schweipert, Markus (2024)
Humane Histondeacetylase 4: Strukturelle Untersuchung des Enzyms und mechanistische Charakterisierung von Inhibitoren.
Technische Universität Darmstadt
doi: 10.26083/tuprints-00028879
Ph.D. Thesis, Primary publication, Publisher's Version

Schweipert, Markus ; Nehls, Thomas ; Frühauf, Anton ; Debarnot, Cecilé ; Kumar, Adarsh ; Knapp, Stefan ; Lermyte, Frederik ; Meyer‐Almes, Franz‐Josef (2024)
The catalytic domain of free or ligand bound histone deacetylase 4 occurs in solution predominantly in closed conformation.
In: Protein Science, 2024, 33 (3)
doi: 10.26083/tuprints-00027114
Article, Secondary publication, Publisher's Version

Schäfer, Sabine Claudia (2024)
Antascomicin B stabilizes FK506-binding protein 51-kinase protein complexes as a molecular glue.
Technische Universität Darmstadt
doi: 10.26083/tuprints-00027005
Ph.D. Thesis, Primary publication, Publisher's Version

Ulitzka, Michael ; Harwardt, Julia ; Lipinski, Britta ; Tran, Hue ; Hock, Björn ; Kolmar, Harald (2024)
Potent Apoptosis Induction by a Novel Trispecific B7-H3xCD16xTIGIT 2+1 Common Light Chain Natural Killer Cell Engager.
In: Molecules, 2024, 29 (5)
doi: 10.26083/tuprints-00027124
Article, Secondary publication, Publisher's Version

Uth, Christina ; Englert, Simon ; Avrutina, Olga ; Kolmar, Harald ; Knauer, Sascha (2024)
Novel amino‐Li resin for water‐based solid‐phase peptide synthesis.
In: Journal of Peptide Science, 2023, 29 (12)
doi: 10.26083/tuprints-00027214
Article, Secondary publication, Publisher's Version

Wack, Julia Susanne (2024)
Peptide und Peptoide als Bindepartner für Chemokine.
Technische Universität Darmstadt
doi: 10.26083/tuprints-00026504
Ph.D. Thesis, Primary publication, Publisher's Version

Wiegand, Pascal (2024)
Molecular epitope and affinity determination of protein-protein interactions by a combination of biosensor and mass spectrometric methods.
Technische Universität Darmstadt
doi: 10.26083/tuprints-00026779
Ph.D. Thesis, Primary publication, Publisher's Version

Zabelskii, D. V. ; Vlasov, A. V. ; Ryzhykau, Yu L. ; Murugova, T. N. ; Brennich, M. ; Soloviov, D. V. ; Ivankov, O. I. ; Borshchevskiy, V. I. ; Mishin, A. V. ; Rogachev, A. V. ; Round, A. ; Dencher, N. A. ; Büldt, G. ; Gordeliy, V. I. ; Kuklin, A. I. (2024)
Ambiguities and completeness of SAS data analysis: investigations of apoferritin by SAXS/SANS EID and SEC-SAXS methods.
In: Journal of Physics: Conference Series, 2018, 994 (1)
doi: 10.26083/tuprints-00020931
Article, Secondary publication, Publisher's Version

Zhou, Xueyuan ; Geyer, Felix Klaus ; Happel, Dominic ; Takimoto, Jeffrey ; Kolmar, Harald ; Rabinovich, Brian (2024)
Using protein geometry to optimize cytotoxicity and the cytokine window of a ROR1 specific T cell engager.
In: Frontiers in Immunology, 2024, 15
doi: 10.26083/tuprints-00027164
Article, Secondary publication, Publisher's Version

2023

Baischew, Asat (2023)
In-cell analysis of FK506 binding protein 51-glucocorticoid receptor-heat shock protein 90 interaction at single residue resolution.
Technische Universität Darmstadt
doi: 10.26083/tuprints-00024106
Ph.D. Thesis, Primary publication, Publisher's Version

Basolli Borsatto, João Victor ; Vasconcelos Soares Maciel, Edvaldo ; Cifuentes, Alejandro ; Lanças, Fernando M. (2023)
Online Extraction Followed by LC-MS/MS Analysis of Lipids in Natural Samples: A Proof-of-Concept Profiling Lecithin in Seeds.
In: Foods, 2023, 12 (2)
doi: 10.26083/tuprints-00023178
Article, Secondary publication, Publisher's Version

Basolli Borsatto, João Victor ; Vasconcelos Soares Maciel, Edvaldo ; Cifuentes, Alejandro ; Lanças, Fernando Mauro (2023)
Applicability and Limitations of a Capillary-LC Column-Switching System Using Hybrid Graphene-Based Stationary Phases.
In: Molecules, 2023, 28 (13)
doi: 10.26083/tuprints-00024253
Article, Secondary publication, Publisher's Version

Bitsch, Sebastian Harald (2023)
Flavors of biotin ligases: From research tools towards biopharmaceutical applications.
Technische Universität Darmstadt
doi: 10.26083/tuprints-00024206
Ph.D. Thesis, Primary publication, Publisher's Version

Bogen, Jan Patrick ; Carrara, Stefania Candela ; Fiebig, David ; Grzeschik, Julius ; Hock, Björn ; Kolmar, Harald (2023)
Supplemental Information with antibody sequences.
doi: 10.26083/tuprints-00017895
Data, Primary publication, Publisher's Version

Carrara, Stefania C. (2023)
Generation of Multispecific Antibodies with Immune Cell Modulating Functions.
Technische Universität Darmstadt
doi: 10.26083/tuprints-00023023
Ph.D. Thesis, Primary publication, Publisher's Version

Duznovic, Ivana ; Gräwe, Alexander ; Weber, Wadim ; Müller, Lena K. ; Ali, Mubarak ; Ensinger, Wolfgang ; Tietze, Alesia ; Stein, Viktor (2023)
Ultrasensitive and Selective Protein Recognition with Nanobody‐Functionalized Synthetic Nanopores.
In: Small : nano micro, 2021, 17 (33)
doi: 10.26083/tuprints-00020980
Article, Secondary publication, Publisher's Version

Harwardt, Julia ; Carrara, Stefania C. ; Bogen, Jan P. ; Schoenfeld, Katrin ; Grzeschik, Julius ; Hock, Björn ; Kolmar, Harald (2023)
Generation of a symmetrical trispecific NK cell engager based on a two-in-one antibody.
In: Frontiers in Immunology, 2023, 14
doi: 10.26083/tuprints-00023673
Article, Secondary publication, Publisher's Version

Heymann, Tim (2023)
Synthesis and mass spectrometry based characterization of chemical tools to explore FK506 binding proteins.
Technische Universität Darmstadt
doi: 10.26083/tuprints-00021441
Ph.D. Thesis, Primary publication, Publisher's Version

Jänsch, Niklas (2023)
Entwicklung neuer Strategien zur spezifischen Hemmung humaner Histondeacetylase 8.
Technische Universität Darmstadt
doi: 10.26083/tuprints-00024434
Ph.D. Thesis, Primary publication, Publisher's Version

Knaup, Fabian Henrik (2023)
Synthesis and investigation of 2-substituted hetero-/arylacetic acids as bottom groups for selective inhibitors of the FK506-binding protein 51 (FKBP51).
Technische Universität Darmstadt
doi: 10.26083/tuprints-00023707
Ph.D. Thesis, Primary publication, Publisher's Version

Kolos, Jürgen (2023)
Synthesis of tailor-made bicyclic [4.3.1] aza-amides.
Technische Universität Darmstadt
doi: 10.26083/tuprints-00017571
Ph.D. Thesis, Primary publication, Publisher's Version

Lipinski, Britta ; Arras, Paul ; Pekar, Lukas ; Klewinghaus, Daniel ; Boje, Ammelie Svea ; Krah, Simon ; Zimmermann, Jasmin ; Klausz, Katja ; Peipp, Matthias ; Siegmund, Vanessa ; Evers, Andreas ; Zielonka, Stefan (2023)
NKp46‐specific single domain antibodies enable facile engineering of various potent NK cell engager formats.
In: Protein Science, 2023, 32 (3)
doi: 10.26083/tuprints-00023690
Article, Secondary publication, Publisher's Version

Liptáková, Veronika (2023)
Antibody-mediated inhibition of MHC class I chain-related protein A shedding for tumor therapy.
Technische Universität Darmstadt
doi: 10.26083/tuprints-00024482
Ph.D. Thesis, Primary publication, Publisher's Version

Nguyen, Melanie ; Le Mignon, Maxime ; Schnellbächer, Alisa ; Wehsling, Maria ; Braun, Julian ; Baumgaertner, Jens ; Grabner, Martina ; Zimmer, Aline (2023)
Mechanistic insights into the biological activity of S-Sulfocysteine in CHO cells using a multi-omics approach.
In: Frontiers in Bioengineering and Biotechnology, 2023, 11
doi: 10.26083/tuprints-00024487
Article, Secondary publication, Publisher's Version

Oliviero, Claudia (2023)
Generation of a Host Cell line containing a MAR-rich landing pad for site specific integration and expression of transgenes.
Technische Universität Darmstadt
doi: 10.26083/tuprints-00026392
Ph.D. Thesis, Primary publication, Publisher's Version

Pitzer, Martin ; Kunitski, Maksim ; Johnson, Allan S. ; Jahnke, Till ; Sann, Hendrik ; Sturm, Felix ; Schmidt, Lothar Ph. H. ; Schmidt-Böcking, Horst ; Dörner, Reinhard ; Stohner, Jürgen ; Kiedrowski, Julia ; Reggelin, Michael ; Marquardt, Sebastian ; Schießer, Alexander ; Berger, Robert ; Schöffler, Markus S. (2023)
Direct Determination of Absolute Molecular Stereochemistry in Gas Phase by Coulomb Explosion Imaging.
In: Science, 2013, 341 (6150)
doi: 10.26083/tuprints-00024248
Article, Secondary publication, Postprint

Purder, Patrick (2023)
Studies on FKBP ligands and inhibitors for GS-like enzymes.
Technische Universität Darmstadt
doi: 10.26083/tuprints-00022875
Ph.D. Thesis, Primary publication, Publisher's Version

Voll, Andreas Markus (2023)
Design, synthesis and biological evaluation of novel FKBP51 ligands.
Technische Universität Darmstadt
doi: 10.26083/tuprints-00017949
Ph.D. Thesis, Primary publication, Publisher's Version

Walz, Michael (2023)
Development of the first selective proteolysis targeting chimera for the FK506-binding protein 51.
Technische Universität Darmstadt
doi: 10.26083/tuprints-00024051
Ph.D. Thesis, Primary publication, Publisher's Version

2022

Ali, Ataurehman (2022)
Analyzing the engineering potential of subtilosin A by probing the substrate promiscuity of the thioether forming sactisynthase AlbA.
Technische Universität Darmstadt
doi: 10.26083/tuprints-00021802
Ph.D. Thesis, Primary publication, Publisher's Version

Ali, Ataurehman ; Happel, Dominic ; Habermann, Jan ; Schoenfeld, Katrin ; Macarrón Palacios, Arturo ; Bitsch, Sebastian ; Englert, Simon ; Schneider, Hendrik ; Avrutina, Olga ; Fabritz, Sebastian ; Kolmar, Harald (2022)
Sactipeptide Engineering by Probing the Substrate Tolerance of a Thioether‐Bond‐Forming Sactisynthase.
In: Angewandte Chemie International Edition, 2022, 61 (45)
doi: 10.26083/tuprints-00022904
Article, Secondary publication, Publisher's Version

Ali, Ataurehman ; Happel, Dominic ; Habermann, Jan ; Schoenfeld, Katrin ; Macarrón Palacios, Arturo ; Bitsch, Sebastian ; Englert, Simon ; Schneider, Hendrik ; Avrutina, Olga ; Fabritz, Sebastian ; Kolmar, Harald (2022)
Untersuchungen zur Substrattoleranz von Sactisynthasen für die Generierung Thioether‐verbrückter Sactipeptide mit neuen Eigenschaften.
In: Angewandte Chemie, 2022, 134 (45)
doi: 10.26083/tuprints-00022902
Article, Secondary publication, Publisher's Version

Bauder, Michael (2022)
Design and Synthesis of macrocyclic FKBP51 ligands.
Technische Universität Darmstadt
doi: 10.26083/tuprints-00018565
Ph.D. Thesis, Primary publication, Publisher's Version

Berthold, Emilia J. ; Ma-Lauer, Yue ; Chakraborty, Ashesh ; Brunn, Brigitte von ; Hilgendorff, Anne ; Hatz, Rudolf ; Behr, Jürgen ; Hausch, Felix ; Staab-Weijnitz, Claudia A. ; Brunn, Albrecht von (2022)
Effects of immunophilin inhibitors and non-immunosuppressive analogs on coronavirus replication in human infection models.
In: Frontiers in Cellular and Infection Microbiology, 2022, 12
doi: 10.26083/tuprints-00022480
Article, Secondary publication, Publisher's Version

Bogorodskiy, Andrey ; Okhrimenko, Ivan ; Burkatovskii, Dmitrii ; Jakobs, Philipp ; Maslov, Ivan ; Gordeliy, Valentin ; Dencher, Norbert A. ; Gensch, Thomas ; Voos, Wolfgang ; Altschmied, Joachim ; Haendeler, Judith ; Borshchevskiy, Valentin (2022)
Role of Mitochondrial Protein Import in Age-Related Neurodegenerative and Cardiovascular Diseases.
In: Cells, 2022, 10 (12)
doi: 10.26083/tuprints-00020276
Article, Secondary publication, Publisher's Version

Carrara, Stefania C. ; Harwardt, Julia ; Grzeschik, Julius ; Hock, Björn ; Kolmar, Harald (2022)
TriTECM: A tetrafunctional T-cell engaging antibody with built-in risk mitigation of cytokine release syndrome.
In: Frontiers in Immunology, 2022, 13
doi: 10.26083/tuprints-00022942
Article, Secondary publication, Publisher's Version

Darvin, Maxim E. ; Lademann, Jürgen ; Hagen, Jörg von ; Lohan, Silke B. ; Kolmar, Harald ; Meinke, Martina C. ; Jung, Sora (2022)
Carotenoids in Human Skin In Vivo: Antioxidant and Photo-Protectant Role against External and Internal Stressors.
In: Antioxidants, 2022, 11 (8)
doi: 10.26083/tuprints-00021856
Article, Secondary publication, Publisher's Version

Djemal, Leila (2022)
Variability and viral safety of cell culture media to ensure process performance in the biopharmaceutical industry.
Technische Universität Darmstadt
doi: 10.26083/tuprints-00020993
Ph.D. Thesis, Primary publication, Publisher's Version

Elter, Adrian Elias Curd ; Bock, Tina ; Spiehl, Dieter ; Russo, Giulio ; Hinz, Steffen C. ; Bitsch, Sebastian ; Baum, Eva ; Langhans, Markus ; Meckel, Tobias ; Dörsam, Edgar ; Kolmar, Harald ; Schwall, Gerhard (2022)
Carbohydrate binding module-fused antibodies improve the performance of cellulose-based lateral flow immunoassays.
In: Scientific Reports, 2022, 11
doi: 10.26083/tuprints-00021201
Article, Secondary publication, Publisher's Version

Fiebig, David ; Bogen, Jan P. ; Carrara, Stefania C. ; Deweid, Lukas ; Zielonka, Stefan ; Grzeschik, Julius ; Hock, Björn ; Kolmar, Harald (2022)
Streamlining the Transition From Yeast Surface Display of Antibody Fragment Immune Libraries to the Production as IgG Format in Mammalian Cells.
In: Frontiers in Bioengineering and Biotechnology, 2022, 10
doi: 10.26083/tuprints-00021336
Article, Secondary publication, Publisher's Version

Harwardt, Julia ; Bogen, Jan P. ; Carrara, Stefania C. ; Ulitzka, Michael ; Grzeschik, Julius ; Hock, Björn ; Kolmar, Harald (2022)
A Generic Strategy to Generate Bifunctional Two-in-One Antibodies by Chicken Immunization.
In: Frontiers in Immunology, 2022, 13
doi: 10.26083/tuprints-00021242
Article, Secondary publication, Publisher's Version

Jäger, Sebastian Michael (2022)
Fc Antigen-Binding Fragment Drug Conjugates as Novel Antibody-Based Format for Targeted Drug Delivery.
Technische Universität Darmstadt
doi: 10.26083/tuprints-00020360
Ph.D. Thesis, Primary publication, Publisher's Version

Kaempffe, Anna (2022)
Evaluation of ADC Physicochemical Characteristics and Their Impact on Pharmacokinetics in Transgenic huFcRn Mice.
Technische Universität Darmstadt
doi: 10.26083/tuprints-00021848
Ph.D. Thesis, Primary publication, Publisher's Version

Kilb, Michelle Fiona ; Moos, Yannik ; Eckes, Stefanie ; Braun, Joy ; Ritz, Ulrike ; Nickel, Daniela ; Schmitz, Katja (2022)
An Additively Manufactured Sample Holder to Measure the Controlled Release of Vancomycin from Collagen Laminates.
In: Biomedicines, 2022, 9 (11)
doi: 10.26083/tuprints-00020067
Article, Secondary publication, Publisher's Version

Klewinghaus, Daniel ; Pekar, Lukas ; Arras, Paul ; Krah, Simon ; Valldorf, Bernhard ; Kolmar, Harald ; Zielonka, Stefan (2022)
Grabbing the Bull by Both Horns: Bovine Ultralong CDR-H3 Paratopes Enable Engineering of ‘Almost Natural’ Common Light Chain Bispecific Antibodies Suitable For Effector Cell Redirection.
In: Frontiers in Immunology, 2022, 12
doi: 10.26083/tuprints-00020369
Article, Secondary publication, Publisher's Version

Lerma Romero, Jorge A. ; Meyners, Christian ; Christmann, Andreas ; Reinbold, Lisa M. ; Charalampidou, Anna ; Hausch, Felix ; Kolmar, Harald (2022)
Binding pocket stabilization by high-throughput screening of yeast display libraries.
In: Frontiers in Molecular Biosciences, 2022, 9
doi: 10.26083/tuprints-00022911
Article, Secondary publication, Publisher's Version

Merz, Stephanie Katharina (2022)
Development and Characterization of a FKBP51FK1 Affinity Matrix for Protein-Protein Interaction Studies.
Technische Universität Darmstadt
doi: 10.26083/tuprints-00022958
Ph.D. Thesis, Primary publication, Publisher's Version

Müller, Sandra Rita (2022)
Validation and characterization of monoclonal antibodies to target cancer stem cells and to develop new anti-cancer therapies.
Technische Universität Darmstadt
doi: 10.26083/tuprints-00021677
Ph.D. Thesis, Primary publication, Publisher's Version

Nehls, Thomas ; Heymann, Tim ; Meyners, Christian ; Hausch, Felix ; Lermyte, Frederik (2022)
Fenton-Chemistry-Based Oxidative Modification of Proteins Reflects Their Conformation.
In: International Journal of Molecular Sciences, 2022, 22 (18)
doi: 10.26083/tuprints-00021257
Article, Secondary publication, Publisher's Version

Oloketuyi, Sandra ; Bernedo, Robert ; Christmann, Andreas ; Borkowska, Justyna ; Cazzaniga, Giulia ; Schuchmann, Horst Wilhelm ; Niedziółka-Jönsson, Joanna ; Szot-Karpińska, Katarzyna ; Kolmar, Harald ; Marco, Ario de (2022)
Native llama Nanobody Library Panning Performed by Phage and Yeast Display Provides Binders Suitable for C-Reactive Protein Detection.
In: Biosensors, 2022, 11 (12)
doi: 10.26083/tuprints-00020274
Article, Secondary publication, Publisher's Version

Purder, Patrick L. ; Meyners, Christian ; Krysenko, Sergii ; Funk, Jonathan ; Wohlleben, Wolfgang ; Hausch, Felix (2022)
Mechanism‐Based Design of the First GlnA4‐Specific Inhibitors.
In: ChemBioChem, 2022, 23 (19)
doi: 10.26083/tuprints-00022898
Article, Secondary publication, Publisher's Version

Wedel, Saskia ; Hahnefeld, Lisa ; Alnouri, Mohamad Wessam ; Offermanns, Stefan ; Hausch, Felix ; Geisslinger, Gerd ; Sisignano, Marco (2022)
The FKBP51 Inhibitor SAFit2 Restores the Pain-Relieving C16 Dihydroceramide after Nerve Injury.
In: International Journal of Molecular Sciences, 2022, 23 (22)
doi: 10.26083/tuprints-00022974
Article, Secondary publication, Publisher's Version

Weiß, Christine Hilde (2022)
Impact of iron on CHO metabolism and recombinant protein production.
Technische Universität Darmstadt
doi: 10.26083/tuprints-00021046
Ph.D. Thesis, Primary publication, Publisher's Version

2021

Becker, Bastian (2021)
Peptide-conjugated dextran hybrids: Generation of a versatile module for cytosolic delivery of biomolecular cargoes.
Technische Universität Darmstadt
doi: 10.26083/tuprints-00019789
Ph.D. Thesis, Primary publication, Publisher's Version

Bogen, Jan P. ; Carrara, Stefania C. ; Fiebig, David ; Grzeschik, Julius ; Hock, Björn ; Kolmar, Harald (2021)
Design of a Trispecific Checkpoint Inhibitor and Natural Killer Cell Engager Based on a 2 + 1 Common Light Chain Antibody Architecture.
In: Frontiers in Immunology, 2021, 12
doi: 10.26083/tuprints-00019364
Article, Secondary publication, Publisher's Version

Bogen, Jan P. ; Carrara, Stefania C. ; Fiebig, David ; Grzeschik, Julius ; Hock, Björn ; Kolmar, Harald (2021)
Expeditious Generation of Biparatopic Common Light Chain Antibodies via Chicken Immunization and Yeast Display Screening.
In: Frontiers in Immunology, 2020, 11
doi: 10.26083/tuprints-00019264
Article, Secondary publication, Publisher's Version

Bogen, Jan Patrick (2021)
Oligospecific Human Antibodies with Therapeutic Potential Derived from Immunized Chickens.
Technische Universität Darmstadt
doi: 10.26083/tuprints-00019360
Ph.D. Thesis, Primary publication, Publisher's Version

Bogen, Jan Patrick ; Grzeschik, Julius ; Jakobsen, Jørn ; Bähre, Alexandra ; Hock, Björn ; Kolmar, Harald (2021)
Treating Bladder Cancer: Engineering of Current and Next Generation Antibody-, Fusion Protein-, mRNA-, Cell- and Viral-Based Therapeutics.
In: Frontiers in Oncology, 2021, 11
doi: 10.26083/tuprints-00019435
Article, Secondary publication, Publisher's Version

Bohländer, Fabian (2021)
The immunomodulatory properties of the IgM- and IgA-enriched immunoglobulin preparation trimodulin.
Technische Universität Darmstadt
doi: 10.26083/tuprints-00019101
Ph.D. Thesis, Primary publication, Publisher's Version

Eckes, Stefanie ; Braun, Joy ; Wack, Julia S. ; Ritz, Ulrike ; Nickel, Daniela ; Schmitz, Katja (2021)
Rose Bengal Crosslinking to Stabilize Collagen Sheets and Generate Modulated Collagen Laminates.
In: International Journal of Molecular Sciences, 2020, 21 (19)
doi: 10.26083/tuprints-00019265
Article, Secondary publication, Publisher's Version

Elter, Adrian ; Yanakieva, Desislava ; Fiebig, David ; Hallstein, Kerstin ; Becker, Stefan ; Betz, Ulrich ; Kolmar, Harald (2021)
Protease-Activation of Fc-Masked Therapeutic Antibodies to Alleviate Off-Tumor Cytotoxicity.
In: Frontiers in Immunology, 2021, 12
doi: 10.26083/tuprints-00019456
Article, Secondary publication, Publisher's Version

Elter, Adrian Elias Curd (2021)
Chicken-derived antibodies for therapeutic, diagnostic and bioprocessing applications.
Technische Universität Darmstadt
doi: 10.26083/tuprints-00019728
Ph.D. Thesis, Primary publication, Publisher's Version

Hinz, Steffen (2021)
Tailor-made antibodies by multidimensional functional screening.
Technische Universität Darmstadt
doi: 10.26083/tuprints-00014598
Ph.D. Thesis, Primary publication, Publisher's Version

Hinz, Steffen C. ; Elter, Adrian ; Rammo, Oliver ; Schwämmle, Achim ; Ali, Ataurehman ; Zielonka, Stefan ; Herget, Thomas ; Kolmar, Harald (2021)
A Generic Procedure for the Isolation of pH- and Magnesium-Responsive Chicken scFvs for Downstream Purification of Human Antibodies.
In: Frontiers in Bioengineering and Biotechnology, 2020, 8
doi: 10.26083/tuprints-00019238
Article, Secondary publication, Publisher's Version

Lermyte, Frederik (2021)
Roles, Characteristics, and Analysis of Intrinsically Disordered Proteins: A Minireview.
In: Life, 2020, 10 (12)
doi: 10.26083/tuprints-00019275
Article, Secondary publication, Publisher's Version

Pekar, Lukas (2021)
Novel technologies for antibody hit discovery and engineering of antibody-like proteins with therapeutic relevance.
Technische Universität Darmstadt
doi: 10.26083/tuprints-00017513
Ph.D. Thesis, Primary publication, Publisher's Version

Schneider, Hendrik ; Englert, Simon ; Macarrón Palacios, Arturo ; Lerma Romero, Jorge Alberto ; Ali, Ataurehman ; Avrutina, Olga ; Kolmar, Harald (2021)
Synthetic Integrin-Targeting Dextran-Fc Hybrids Efficiently Inhibit Tumor Proliferation In Vitro.
In: Frontiers in Chemistry, 2021, 9
doi: 10.26083/tuprints-00019401
Article, Secondary publication, Publisher's Version

Yanakieva, Desislava ; Elter, Adrian ; Bratsch, Jens ; Friedrich, Karlheinz ; Becker, Stefan ; Kolmar, Harald (2021)
FACS-Based Functional Protein Screening via Microfluidic Co-encapsulation of Yeast Secretor and Mammalian Reporter Cells.
In: Scientific Reports, 2020, (10)
doi: 10.26083/tuprints-00018649
Article, Secondary publication, Publisher's Version

Zimmermann, Martina (2021)
The impact of S-sulfocysteine in cell culture media.
Technische Universität Darmstadt
doi: 10.26083/tuprints-00014299
Ph.D. Thesis, Primary publication, Publisher's Version

2020

Anderl, Anita (2020)
Charakterisierung von Zellwandproteinen des Transglutaminase-Produzenten Streptomyces mobaraensis.
Technische Universität Darmstadt
doi: 10.25534/tuprints-00011585
Ph.D. Thesis, Primary publication

Brahm, Kevin (2020)
Untersuchung von Peptidomimetika als Inhibitoren für das Chemokin CXCL8.
Technische Universität Darmstadt
doi: 10.25534/tuprints-00011794
Ph.D. Thesis, Primary publication

Haehle, Andreas (2020)
Elucidation of the molecular and cellular mechanisms of FKBP51-selective inhibitors.
Technische Universität Darmstadt
doi: 10.25534/tuprints-00013235
Ph.D. Thesis, Primary publication

Hofmann, Tim Lothar (2020)
Intein mediated high throughput screening for bispecific antibodies.
Technische Universität Darmstadt
doi: 10.25534/tuprints-00013280
Ph.D. Thesis, Primary publication, Publisher's Version

Mao, Tianqi (2020)
Development of Novel Small-Molecule Degraders of FK506-Binding Protein 51.
Technische Universität Darmstadt
doi: 10.25534/tuprints-00011503
Ph.D. Thesis, Primary publication

Rieker, Marcel (2020)
Targeted Combination Therapy: Discovery and Evaluation of Synergistic Anticancer Effects of Anti-HER2-Duocarmycin Antibody-Drug Conjugates Combined with ATR Inhibitors.
Technische Universität Darmstadt
doi: 10.25534/tuprints-00008615
Ph.D. Thesis, Primary publication

Sapir, Ashi (2020)
Evaluation of Yeast Display Fab Libraries Derived from Tumor Infiltrating B Cells.
Technische Universität Darmstadt
doi: 10.25534/tuprints-00011371
Ph.D. Thesis, Primary publication

Schmidt, Carolin (2020)
Functional characterization of a new IgM- and IgA-enriched immunoglobulin preparation.
Technische Universität Darmstadt
doi: 10.25534/tuprints-00015398
Ph.D. Thesis, Primary publication, Publisher's Version

Schneider, Hendrik Peter Günter (2020)
Multivalent Functionalized Dextran-Antibody Conjugates for Efficient Tumor Cell Killing.
Technische Universität Darmstadt
doi: 10.25534/tuprints-00011502
Ph.D. Thesis, Primary publication

Yanakieva, Desislava (2020)
Ultra-High-Throughput Single-Cell Functional Screening by Combination of Microfluidics and GMD-FACS.
Technische Universität Darmstadt
doi: 10.25534/tuprints-00013464
Ph.D. Thesis, Primary publication

2019

Ebenig, Aileen (2019)
Biopolymeric scaffold to achieve high drug-to-antibody ratios using site specific conjugation strategies.
Technische Universität Darmstadt
Ph.D. Thesis, Primary publication

Fiebig, David Alexander (2019)
Das Dispaseautolyse-induzierende Protein von Streptomyces mobaraensis. Struktur, Katalysemechanismus und Glutaminbindestellen für die Modifikation durch mikrobielle Transglutaminase.
Technische Universität Darmstadt
Ph.D. Thesis, Primary publication

Geiger, Thomas M. ; Hähle, Andreas ; Merz, Stephanie ; Meyners, Christian ; Tianqi, Mao ; Kolos, Jürgen ; Hausch, Felix (2019)
FKBP51 and FKBP12.6—Novel and tight interactors of Glomulin.
In: PLOS ONE, 2019, 14 (9)
Article, Secondary publication, Publisher's Version

Kolos, Jürgen M. ; Voll, Andreas M. ; Bauder, Michael ; Hausch, Felix (2019)
FKBP Ligands—Where We Are and Where to Go?
In: Frontiers in Pharmacology, 2018, 9
Article, Secondary publication, Publisher's Version

Mang, Tanja (2019)
Evaluation of the therapeutic potential of GDF5 mutants to treat osteoarthritis.
Technische Universität Darmstadt
Ph.D. Thesis, Primary publication

Mueller, Lena (2019)
Chemical synthesis of switchable peptide-based nanopores: from ion channels to bio-inspired materials.
Technische Universität Darmstadt
doi: 10.25534/tuprints-00011495
Ph.D. Thesis, Primary publication

Roßkopf, Janis Mario (2019)
Improved Drug Delivery of next-generation Antibody-Drug Conjugates by utilizing tumor-associated proteases.
Technische Universität Darmstadt
doi: 10.25534/tuprints-00009685
Ph.D. Thesis, Primary publication

Rutkowski, Emilia (2019)
Erstcharakterisierung des C‐Typ Lektin‐ähnlichen Glykoproteins Clr‐a.
Technische Universität Darmstadt
Ph.D. Thesis, Primary publication

2018

Pirzer, Thomas (2018)
Generation of anti-HER1/2 immunotoxins by protein ligation using split inteins.
Technische Universität Darmstadt
Ph.D. Thesis, Primary publication

Winterling, Karina (2018)
Immunogenic Determinants of Coagulation Factor VIII.
Technische Universität Darmstadt
Ph.D. Thesis, Primary publication

2017

Džinić, Tamara (2017)
Interplay of ionizing radiation, oxygen, ROS and age-associated diseases.
Technische Universität Darmstadt
Ph.D. Thesis, Primary publication

Hörner, Sebastian (2017)
Biofunctionalization of Silsesquioxane Nanoparticles.
Technische Universität Darmstadt
Ph.D. Thesis, Primary publication

Meyners, Christian Stephan (2017)
Selectivity in histone deacetylase inhibition: A biophysical approach.
Technische Universität Darmstadt
Ph.D. Thesis, Primary publication

Schirmer, Matthias (2017)
Erschließung einer natürlichen Peptid-Protein-Wechselwirkung als molekulare Grundstruktur zur hochaffinen Kopplung von Proteinen und Entwicklung biotechnologischer Anwendungsmodule.
Technische Universität Darmstadt
Ph.D. Thesis, Primary publication

Schnellbächer, Mark (2017)
Kinetische und präparative Studien mit neuen Sialinsäuresynthasen aus Neisseria meningitidis und Campylobacter jejuni.
Technische Universität Darmstadt
Ph.D. Thesis, Primary publication

Steinhäuser, Kerstin (2017)
Funktion und Regulation des neuen Tubulin-assoziierten Proteins RITA.
Technische Universität Darmstadt
Ph.D. Thesis, Primary publication

Weber, Niklas (2017)
Structure-Based Monomerization of Human Serine Protease HTRA1 towards Evolutive Engineering of Activity Modulators.
Technische Universität Darmstadt
Ph.D. Thesis, Primary publication

2016

Decker, Victoria (2016)
Beeinflussung von Zellphysiologie und mitochondrialer Funktion durch Alzheimer Demenz-assoziiertes Amyloides-β Peptid.
Technische Universität Darmstadt
Ph.D. Thesis, Primary publication

Fittler, Heiko (2016)
Peptidic inhibitors of therapeutically relevant proteases: Design, synthesis, and functional evaluation.
Technische Universität Darmstadt
Ph.D. Thesis, Primary publication

Husslik, Felix (2016)
Analysis of the IgE epitope profile of the soybean allergen Gly m 4.
Technische Universität Darmstadt
Ph.D. Thesis, Primary publication

Jöst, Marina (2016)
Etablierung von zellbasierten Assays zur Identifizierung von Inhibitoren des Chemokins CXCL8.
Technische Universität Darmstadt
Ph.D. Thesis, Primary publication

Kratochwil, Manuela (2016)
Effects of ageing, calorie restriction and ageing-associated diseases on the mitochondrial proteome.
Technische Universität Darmstadt
Ph.D. Thesis, Primary publication

Nasu, Daichi (2016)
Non-Natural Elements for Peptide-Based Molecular Design, Structural Analysis, and Functional Modifications.
Technische Universität Darmstadt
Ph.D. Thesis, Primary publication

Rink, Ina (2016)
Untersuchungsmethoden für die chemokininduzierte Migration von Leukozyten.
Technische Universität Darmstadt
Ph.D. Thesis, Primary publication

Sellmann, Carolin (2016)
Balancing Efficacy and Selectivity of Bispecific c-METxEGFR Antibodies.
Technische Universität Darmstadt
Ph.D. Thesis, Primary publication

Uth, Christina (2016)
Development of bioorthogonal synthetic strategies towards hybrid macromolecular conjugates with tailored properties.
Technische Universität Darmstadt
Ph.D. Thesis, Primary publication

Valldorf, Bernhard (2016)
Multivalent display of functional biomacromolecules: a modular approach.
Technische Universität Darmstadt
Ph.D. Thesis, Primary publication

2015

Cavlovic, Lidija (2015)
Wirkung von ionisierender Strahlung auf Proteom und Lipidom sowie auf zelluläre und mitochondriale Aktivität.
Technische Universität Darmstadt
Ph.D. Thesis, Primary publication

Korbus, Michael (2015)
Entwicklung und Charakterisierung einer photoschaltbaren Histondeacetylase-ähnlichen Amidohydrolase.
Technische Universität Darmstadt
Ph.D. Thesis, Primary publication

Loggen, Franziska (2015)
Über die Etablierung neuartiger Verfahren zur DNA vermittelten in vitro Genotyp-Phänotyp-Kopplung.
Technische Universität Darmstadt
Ph.D. Thesis, Primary publication

Zielonka, Stefan (2015)
The shark strikes twice: Generation of Mono- and Bispecific High-Affinity vNAR Antibody Domains via Step-Wise Affinity Maturation.
Technische Universität Darmstadt
Ph.D. Thesis, Primary publication

2014

Capito, Florian (2014)
Development and monitoring of a novel monoclonal antibody purification strategy.
Technische Universität Darmstadt
Ph.D. Thesis, Primary publication

Hofmann, Monika (2014)
Influence of the Maillard reaction on the allergenicity of food allergens.
Technische Universität Darmstadt
Ph.D. Thesis, Primary publication

Maaß, Franziska (2014)
Protein Engineering an Cystinknoten-Miniproteinen: Generierung von immunregulatorischen Varianten mit optimierten Bindungseigenschaften und Gerüststrukturen.
Technische Universität Darmstadt
Ph.D. Thesis, Primary publication

Wohlmann, Andreas (2014)
Signaltransduktion, spezifische Hemmung und biotechnologische Anwendung des humanen TSLP-Rezeptors.
Technische Universität Darmstadt
Ph.D. Thesis, Primary publication

2013

Bauch, Caroline D. (2013)
Development and validation of animal-free test methods to predict the skin sensitizing potential of chemicals.
Technische Universität Darmstadt
Ph.D. Thesis, Primary publication

Empting, Martin (2013)
Disubstituted 1,2,3-Triazoles: A Multitool for Biomolecular Chemistry.
Technische Universität Darmstadt
Ph.D. Thesis, Primary publication

Fabritz, Sebastian (2013)
Bioconjugation of Peptides on Cube-octameric Silsesquioxanes.
Technische Universität Darmstadt
Ph.D. Thesis, Primary publication

Glotzbach, Bernhard (2013)
Isolierung und Charakterisierung hochaffiner Cystinknoten- basierter Matriptase-1 Inhibitoren.
Technische Universität Darmstadt
Ph.D. Thesis, Primary publication

Hofmeyer, Thomas (2013)
Über die Charakterisierung und funktionelle Produktion der Oligomerisierungsdomäne des humanen C4b-Bindeproteins.
Technische Universität Darmstadt
Ph.D. Thesis, Primary publication

Thilmany, Sandra Cornelia (2013)
Das mitochondriale Proteom von Rattus norvegicus in Abhängigkeit von Alter und Kalorienrestriktion.
Technische Universität Darmstadt
Ph.D. Thesis, Primary publication

Tomaszowski, Michael (2013)
Neue Miniproteininhibitoren gegen die humane Typ II Transmembranserinprotease Matriptase (MT-SPI).
Technische Universität Darmstadt
Ph.D. Thesis, Primary publication

Zindel, Stephan (2013)
Struktur und Funktion enzymatisch vernetzbarer Proteaseinhibitoren von Streptomyces mobaraensis.
Technische Universität Darmstadt
Ph.D. Thesis, Primary publication

2012

Frenzel, Monika (2012)
Mitochondrial ageing in rat brain areas and human fibroblasts.
Technische Universität Darmstadt
Ph.D. Thesis, Primary publication

Heil, Stefanie (2012)
Evolutive Optimierung mikrobieller Lipasen und Esterasen in Hinblick auf Substratspezifität und Enantioselektivität.
Technische Universität Darmstadt
Ph.D. Thesis, Primary publication

Schäfer, Eva Regine (2012)
Massenspektrometrische und gelelektrophoretische Analyse altersabhängiger Veränderungen des mitochondrialen Proteoms von Modellorganismen.
Technische Universität Darmstadt
Ph.D. Thesis, Primary publication

2011

Boltz, Achim (2011)
Bi-specific Aptamers mediating Tumour Cell Lysis.
Technische Universität Darmstadt
Ph.D. Thesis, Primary publication

Heidrich, Nicolas Georges (2011)
Superkomplexe aus Algen und Cyanobakterien - Isolierung, Charakterisierung und strukturelle Untersuchung.
Technische Universität Darmstadt
Ph.D. Thesis, Primary publication

2010

Schwaßmann, Helena J. (2010)
Analyse von Atmungskettenkomplexen aus Organellen von Chlamydomonas reinhardtii und Rattus norvegicus.
Technische Universität Darmstadt
Ph.D. Thesis, Primary publication