2023

Zong, Dali ; Jakob, Burkhard ; Lundholm, Lovisa (2023):
Editorial: DNA damage response in the context of chromatin. (Publisher's Version)
In: Frontiers in Cell and Developmental Biology, 10, Frontiers Media S.A., e-ISSN 2296-634X,
DOI: 10.26083/tuprints-00023125,
[Article]

2022

Averbeck, Nicole B. ; Barent, Carina ; Jakob, Burkhard ; Syzonenko, Tatyana ; Durante, Marco ; Taucher-Scholz, Gisela (2022):
The Ubiquitin Ligase RNF138 Cooperates with CtIP to Stimulate Resection of Complex DNA Double-Strand Breaks in Human G1-Phase Cells. (Publisher's Version)
In: Cells, 11 (16), MDPI, e-ISSN 2073-4409,
DOI: 10.26083/tuprints-00022312,
[Article]

Brackmann, Lara Kim ; Foraita, Ronja ; Schwarz, Heike ; Galetzka, Danuta ; Zahnreich, Sebastian ; Hankeln, Thomas ; Löbrich, Markus ; Poplawski, Alicia ; Grabow, Desiree ; Blettner, Maria ; Schmidberger, Heinz ; Marron, Manuela (2022):
Late health effects and changes in lifestyle factors after cancer in childhood with and without subsequent second primary cancers – the KiKme case-control study. (Publisher's Version)
In: Frontiers in Oncology, 12, Frontiers Media S.A., e-ISSN 2234-943X,
DOI: 10.26083/tuprints-00022577,
[Article]

Ensminger, Michael ; Iloff, Lucie ; Ebel, Christian ; Nikolova, Teodora ; Kaina, Bernd ; Löbrich, Markus (2022):
DNA breaks and chromosomal aberrations arise when replication meets base excision repair. (Publisher's Version)
In: Journal of Cell Biology, 206 (1), pp. 29-43. Rockefeller University Press, ISSN 0021-9525, e-ISSN 1540-8140,
DOI: 10.26083/tuprints-00018940,
[Article]

Freund, Isabel (2022):
Nek1 - developmental involvement in DNA repair and role as a target in radiotherapy. (Publisher's Version)
Darmstadt, Technische Universität,
DOI: 10.26083/tuprints-00021560,
[Ph.D. Thesis]

Goetting, Isabell ; Larafa, Safa ; Eul, Katharina ; Kunin, Mikhail ; Jakob, Burkhard ; Matschke, Johann ; Jendrossek, Verena (2022):
Targeting AKT-Dependent Regulation of Antioxidant Defense Sensitizes AKT-E17K Expressing Cancer Cells to Ionizing Radiation. (Publisher's Version)
In: Frontiers in Oncology, 12, Frontiers Media S.A., e-ISSN 2234-943X,
DOI: 10.26083/tuprints-00021747,
[Article]

Jakob, Burkhard ; Splinter, Jörn ; Conrad, Sandro ; Voss, Kay-Obbe ; Zink, Daniele ; Durante, Marco ; Löbrich, Markus ; Taucher-Scholz, Gisela (2022):
DNA double-strand breaks in heterochromatin elicit fast repair protein recruitment, histone H2AX phosphorylation and relocation to euchromatin. (Publisher's Version)
In: Nucleic Acids Research, 39 (15), pp. 6489-6499. Oxford University Press, ISSN 0305-1048, e-ISSN 1362-4962,
DOI: 10.26083/tuprints-00019032,
[Article]

Kakarougkas, Andreas ; Ismail, Amani ; Klement, Karolin ; Goodarzi, Aaron A. ; Conrad, Sandro ; Freire, Raimundo ; Shibata, Atsushi ; Löbrich, Markus ; Jeggo, Penny A. (2022):
Opposing roles for 53BP1 during homologous recombination. (Publisher's Version)
In: Nucleic Acids Research, 41 (21), pp. 9719-9731. Oxford University Press, ISSN 0305-1048, e-ISSN 1362-4962,
DOI: 10.26083/tuprints-00019031,
[Article]

Pfeffel, Daniel (2022):
Investigating the interplay of replication, transcription, and BER for the induction of DSBs after oxidative stress. (Publisher's Version)
Darmstadt, Technische Universität Darmstadt,
DOI: 10.26083/tuprints-00022399,
[Ph.D. Thesis]

Quennet, Verena ; Beucher, Andrea ; Barton, Olivia ; Takeda, Shunichi ; Löbrich, Markus (2022):
CtIP and MRN promote non-homologous end-joining of etoposide-induced DNA double-strand breaks in G1. (Publisher's Version)
In: Nucleic Acids Research, 39 (6), pp. 2144-2152. Oxford University Press, ISSN 0305-1048, e-ISSN 1362-4962,
DOI: 10.26083/tuprints-00019509,
[Article]

Smit, Timo Eric (2022):
Kardiotoxizität weltraumrelevanter Schwerionenstrahlung: In vitro Effekte auf Funktion und Pathophysiologie von Kardiomyozyten. (Publisher's Version)
Darmstadt, Technische Universität,
DOI: 10.26083/tuprints-00020924,
[Ph.D. Thesis]

Thomas, Holly (2022):
Investigating the importance of RAD54 and NEK1 in homologous recombination within the developing mouse. (Publisher's Version)
Darmstadt, Technische Universität Darmstadt,
DOI: 10.26083/tuprints-00022952,
[Ph.D. Thesis]

Wei, Na (2022):
RNA involvement during non-homologous end joining of resected DNA double strand breaks in G1. (Publisher's Version)
Darmstadt, Technical University of Darmstadt,
DOI: 10.26083/tuprints-00021565,
[Ph.D. Thesis]

2021

Averbek, Sera (2021):
Effects of O-GlcNAcylation on radiation-induced DNA double-strand break repair. (Publisher's Version)
Darmstadt, Technische Universität Darmstadt,
DOI: 10.26083/tuprints-00020192,
[Ph.D. Thesis]

Barton, Olivia ; Naumann, Steffen C. ; Diemer-Biehs, Ronja ; Künzel, Julia ; Steinlage, Monika ; Conrad, Sandro ; Makharashvili, Nodar ; Wang, Jiadong ; Feng, Lin ; Lopez, Bernard S. ; Paull, Tanya T. ; Chen, Junjie ; Jeggo, Penny A. ; Löbrich, Markus (2021):
Polo-like kinase 3 regulates CtIP during DNA double-strand break repair in G1. (Publisher's Version)
In: Journal of Cell Biology, 206 (7), pp. 877-894. Rockefeller University Press, ISSN 0021-9525, e-ISSN 1540-8140,
DOI: 10.26083/tuprints-00018937,
[Article]

Biehs, Ronja ; Steinlage, Monika ; Barton, Olivia ; Juhász, Szilvia ; Künzel, Julia ; Spies, Julian ; Shibata, Atsushi ; Jeggo, Penny A. ; Löbrich, Markus (2021):
DNA Double-Strand Break Resection Occurs during Non-homologous End Joining in G1 but Is Distinct from Resection during Homologous Recombination. (Publisher's Version)
In: Molecular Cell, 65 (4), pp. 671-684. Elsevier, ISSN 1097-2765,
DOI: 10.26083/tuprints-00013323,
[Article]

Conrad, Sandro ; Künzel, Julia ; Löbrich, Markus (2021):
Sister chromatid exchanges occur in G₂-irradiated cells. (Publisher's Version)
In: Cell Cycle, 10 (2), pp. 222-228. Taylor and Francis Group, ISSN 1538-4101, e-ISSN 1551-4005,
DOI: 10.26083/tuprints-00019036,
[Article]

Deckbar, Dorothee ; Jeggo, Penny A. ; Löbrich, Markus (2021):
Understanding the limitations of radiation-induced cell cycle checkpoints. (Publisher's Version)
In: Critical Reviews in Biochemistry and Molecular Biology, 46 (4), pp. 271-283. Taylor and Francis Group, ISSN 1040-9238, e-ISSN 1549-7798,
DOI: 10.26083/tuprints-00019037,
[Article]

Elbakry, Amira (2021):
Factors regulating late stages of homologous recombination and sub-pathway choice in G2. (Publisher's Version)
Darmstadt, Technische Universität Darmstadt,
DOI: 10.26083/tuprints-00017575,
[Ph.D. Thesis]

Elbakry, Amira ; Juhász, Szilvia ; Chan, Ki Choi ; Löbrich, Markus (2021):
ATRX and RECQ5 define distinct homologous recombination subpathways. (Publisher's Version)
In: Proceedings of the National Academy of Sciences of the United States of America, 118 (3), National Academy of Sciences, ISSN 0027-8424, e-ISSN 1091-6490,
DOI: 10.26083/tuprints-00018942,
[Article]

Elbakry, Amira ; Juhász, Szilvia ; Mathes, Arthur ; Löbrich, Markus (2021):
DNA repair synthesis and histone deposition partner during homologous recombination. (Publisher's Version)
In: Molecular & Cellular Oncology, 5 (5), Taylor & Francis, e-ISSN 2372-3556,
DOI: 10.26083/tuprints-00019061,
[Article]

Elbakry, Amira ; Löbrich, Markus (2021):
Homologous Recombination Subpathways: A Tangle to Resolve. (Publisher's Version)
In: Frontiers in Genetics, 12, Frontiers, e-ISSN 1664-8021,
DOI: 10.26083/tuprints-00019438,
[Article]

Ensminger, Michael ; Löbrich, Markus (2021):
One end to rule them all: Non-homologous end-joining and homologous recombination at DNA double-strand breaks. (Publisher's Version)
In: The British Journal of Radiology, 93 (1115), British Institute of Radiology, ISSN 0007-1285, e-ISSN 1748-880X,
DOI: 10.26083/tuprints-00018929,
[Article]

Fischer, Ulrike ; Rheinheimer, Stefanie ; Krempler, Andrea ; Löbrich, Markus ; Meese, Eckart (2021):
Glioma-amplified sequence KUB3 influences double-strand break repair after ionizing radiation. (Publisher's Version)
In: International Journal of Oncology, 43 (1), pp. 50-56. Spandidos Publications, ISSN 1019-6439, e-ISSN 1791-2423,
DOI: 10.26083/tuprints-00019034,
[Article]

Freund, Isabel ; Hehlgans, Stephanie ; Martin, Daniel ; Ensminger, Michael ; Fokas, Emmanouil ; Rödel, Claus ; Löbrich, Markus ; Rödel, Franz (2021):
Fractionation-Dependent Radiosensitization by Molecular Targeting of Nek1. (Publisher's Version)
In: Cells, 9 (5), MDPI, e-ISSN 2073-4409,
DOI: 10.26083/tuprints-00019029,
[Article]

Frohns, Florian ; Frohns, Antonia ; Kramer, Johanna ; Meurer, Katharina ; Rohrer-Bley, Carla ; Solovei, Irina ; Hicks, David ; Layer, Paul G. ; Löbrich, Markus (2021):
Differences in the Response to DNA Double-Strand Breaks between Rod Photoreceptors of Rodents, Pigs, and Humans. (Publisher's Version)
In: Cells, 9 (4), MDPI, e-ISSN 2073-4409,
DOI: 10.26083/tuprints-00019030,
[Article]

Geuting, Verena ; Reul, Christian ; Löbrich, Markus (2021):
ATM Release at Resected Double-Strand Breaks Provides Heterochromatin Reconstitution to Facilitate Homologous Recombination. (Publisher's Version)
In: PLOS Genetics, 9 (8), PLOS, ISSN 1553-7390, e-ISSN 1553-7404,
DOI: 10.26083/tuprints-00019033,
[Article]

Jeggo, Penny A. ; Löbrich, Markus (2021):
DNA non-homologous end-joining enters the resection arena. (Publisher's Version)
In: Oncotarget, 8 (55), pp. 93317-93318. Impact Journals, e-ISSN 1949-2553,
DOI: 10.26083/tuprints-00019062,
[Article]

Kakarougkas, Andreas ; Ismail, Amani ; Chambers, Anna L. ; Riballo, Enriqueta ; Herbert, Alex D. ; Künzel, Julia ; Löbrich, Markus ; Jeggo, Penny A. ; Downs, Jessica A. (2021):
Requirement for PBAF in Transcriptional Repression and Repair at DNA Breaks in Actively Transcribed Regions of Chromatin. (Publisher's Version)
In: Molecular Cell, 55 (5), pp. 723-732. Elsevier, ISSN 1097-2765,
DOI: 10.26083/tuprints-00018938,
[Article]

Lengert, Nicor ; Mirsch, Johanna ; Weimer, Ratna N. ; Schumann, Eik ; Haub, Peter ; Drossel, Barbara ; Löbrich, Markus (2021):
AutoFoci, an automated high-throughput foci detection approach for analyzing low-dose DNA double-strand break repair. (Publisher's Version)
In: Scientific Reports, 8 (1), Springer Nature, e-ISSN 2045-2322,
DOI: 10.26083/tuprints-00019035,
[Article]

Löbrich, Markus ; Jeggo, Penny (2021):
A Process of Resection-Dependent Nonhomologous End Joining Involving the Goddess Artemis. (Publisher's Version)
In: Trends in Biochemical Sciences, 42 (9), pp. 690-701. Elsevier, ISSN 0968-0004,
DOI: 10.26083/tuprints-00018935,
[Article]

Löbrich, Markus ; Shibata, Atsushi ; Beucher, Andrea ; Fisher, Anna ; Ensminger, Michael ; Goodarzi, Aaron A. ; Barton, Olivia ; Jeggo, Penny A. (2021):
γH2AX foci analysis for monitoring DNA double-strand break repair: Strengths, limitations and optimization. (Publisher's Version)
In: Cell Cycle, 9 (4), pp. 662-669. Taylor and Francis Group, ISSN 1538-4101, e-ISSN 1551-4005,
DOI: 10.26083/tuprints-00019060,
[Article]

Mirsch, Johanna ; Hintz, Lisa ; Maier, Andreas ; Fournier, Claudia ; Löbrich, Markus (2021):
An Assessment of Radiation Doses From Radon Exposures Using a Mouse Model System. (Publisher's Version)
In: International Journal of Radiation Oncology*Biology*Physics, 108 (3), pp. 770-778. Elsevier, ISSN 0360-3016,
DOI: 10.26083/tuprints-00018931,
[Article]

Shibata, Atsushi ; Jeggo, Penny ; Löbrich, Markus (2021):
The pendulum of the Ku-Ku clock. (Publisher's Version)
In: DNA Repair, 71, pp. 164-171. Elsevier, ISSN 1568-7864,
DOI: 10.26083/tuprints-00018932,
[Article]

Wang, Jiadong ; Aroumougame, Asaithamby ; Löbrich, Markus ; Li, Yujing ; Chen, David ; Chen, Junjie ; Gong, Zihua (2021):
PTIP associates with Artemis to dictate DNA repair pathway choice. (Publisher's Version)
In: Genes & Development, 28 (24), pp. 2693-2698. Cold Spring Harbor Laboratory Press, ISSN 0890-9369, e-ISSN 1549-5477,
DOI: 10.26083/tuprints-00018930,
[Article]

Zahnreich, Sebastian ; Poplawski, Alicia ; Hartel, Carola ; Eckhard, Lukas Stefan ; Galetzka, Danuta ; Hankeln, Thomas ; Löbrich, Markus ; Marron, Manuela ; Mirsch, Johanna ; Ritter, Sylvia ; Scholz-Kreisel, Peter ; Spix, Claudia ; Schmidberger, Heinz (2021):
Spontaneous and Radiation-Induced Chromosome Aberrations in Primary Fibroblasts of Patients With Pediatric First and Second Neoplasms. (Publisher's Version)
In: Frontiers in Oncology, 10, Frontiers, e-ISSN 2234-943X,
DOI: 10.26083/tuprints-00018936,
[Article]

2020

Barent, Carina (2020):
Relevanz der Ubiquitinierung für die Resektionsregulation in G1-Phase-Zellen an schwerioneninduzierten DNA-Doppelstrangbrüchen.
Darmstadt, Technische Universität Darmstadt,
DOI: 10.25534/tuprints-00011439,
[Ph.D. Thesis]

Güllülü, Ömer (2020):
Spatial and functional interrelationship of a heterotetramer Survivin-DNA-PKcs complex in the repair of DNA double-strand breaks. (Publisher's Version)
Darmstadt, Technische Universität,
DOI: 10.25534/tuprints-00015406,
[Ph.D. Thesis]

2019

Köhler, Tim (2019):
Auswirkungen elektromagnetischer Strahlung auf die elektrophysiologischen Eigenschaften neuronaler und kardialer Zellnetzwerke.
Darmstadt, Technische Universität,
[Ph.D. Thesis]

2018

Gawai, Anugrah (2018):
Characterization of Rad52 protein function during DNA double-strand break repair in G2 phase mammalian cells.
Darmstadt, Technische Universität,
[Ph.D. Thesis]

Syzonenko, Tatyana (2018):
Investigations to the DNA resection regulation of ion-induced DSBs in G1 cells and the resection limitations of the cells in quiescent state.
Darmstadt, Technische Universität,
[Ph.D. Thesis]

2017

Anugwom (geb. Biehs), Ronja (2017):
Resection-dependent canonical non-homologous end-joining induces genomic rearrangements.
Darmstadt, Technische Universität,
[Ph.D. Thesis]

Erbeldinger, Nadine (2017):
Microvascular Damage as Initial Event of Scar Formation after Carbon Ion Irradiation of Cardiac Substructures.
Darmstadt, Technische Universität,
[Ph.D. Thesis]

Mayer, Margot (2017):
Einfluss ionisierender Strahlung auf die elektrophysiologischen Eigenschaften sich entwickelnder neuronaler Netzwerke.
Darmstadt, Technische Universität,
[Ph.D. Thesis]

Mirsch, Johanna (2017):
Biologischer Nachweis niedriger Dosen ionisierender Strahlung.
Darmstadt, Technische Universität,
[Ph.D. Thesis]

Mofidi, Amir (2017):
DNA-double strand break repair and cell cycle control of murine stem cells after exposure to ionizing radiation.
Darmstadt, Technische Universität,
[Ph.D. Thesis]

Shreder, Kateryna (2017):
Impact of ionizing radiation on adipokine-induced inflammation in musculoskeletal diseases (MSD): Investigations in primary cells and MSD patients.
Darmstadt, Technische Universität,
[Ph.D. Thesis]

Steinlage, Monika (2017):
Characterization of the slow DNA double-strand break repair component in G1 phase.
Darmstadt, Technische Universität,
[Ph.D. Thesis]

2016

Waizenegger, Anja (2016):
Investigation of factors involved in late stages of homologous recombination.
Darmstadt, Technische Universität Darmstadt,
[Ph.D. Thesis]

Wess, Johannes (2016):
Untersuchungen zur Prozessierung von Intermediaten der DNA-Doppelstrangbruchreparatur in der Mitose nach Bestrahlung in der G2-Phase.
Darmstadt, Technische Universität Darmstadt,
[Ph.D. Thesis]

Wiedemann, Julia (2016):
Untersuchung von entzündungsrelevanter interzellulärer Kommunikation nach Bestrahlung in einem 3D-Haut-Modell.
Darmstadt, Technische Universität Darmstadt,
[Ph.D. Thesis]

2015

Knorr, Sabine (2015):
In Silico Strategies to Modulate DNA Damage Response.
Darmstadt, Technische Universität,
[Ph.D. Thesis]

Large, Martin (2015):
Cellular and molecular aspects of the anti-inflammatory effects of low-dose radiation therapy.
Darmstadt, Technische Universität,
[Ph.D. Thesis]

Lengert, Laurin (2015):
Theoretische und experimentelle Methoden zur Verbesserung der Unterscheidbarkeit alternativer Modelle der Proteinrekrutierung.
Darmstadt, Technische Universität,
[Ph.D. Thesis]

Maier, Andreas (2015):
Entwicklung einer Radonkammer und Messung der Radonlöslichkeit in Gewebe.
Darmstadt, Technische Universität,
[Ph.D. Thesis]

Spies, Julian (2015):
Die Beteiligung von Nek1 an der Homologen Rekombination.
Darmstadt, Technische Universität,
[Ph.D. Thesis]

Taubmann, Andreas (2015):
Untersuchung der DNA-Doppelstrangbruch-Reparatur über Homologe Rekombination am Übergang von der G2-Phase in die Mitose.
Darmstadt, Technische Universität,
[Ph.D. Thesis]

2014

Becker, Linda Carmen Annabelle (2014):
Influence of repair proteins and chromatin modifiers on mobility of DNA double-strand breaks induced by heavy ion irradiation.
Darmstadt, Technische Universität,
[Ph.D. Thesis]

Herrlitz, Maren Linda (2014):
Elucidation of DNA methylation changes in response to ionizing radiation induced double strand breaks.
Darmstadt, Technische Universität,
[Ph.D. Thesis]

Iloff, Lucie (2014):
Untersuchungen zur Induktion und Reparatur von DNA-Schäden durch Hydroxyurea.
Darmstadt, Technische Universität,
[Ph.D. Thesis]

Krasnyanska, Julia (2014):
DNA‐Doppelstrangbruchreparatur im DT40‐Zellsystem.
Darmstadt, Technische Universität,
[Ph.D. Thesis]

Längle, Adriana (2014):
Ionotrope Glutamatrezeptoren als Targetstrukturen zur Modulation der Strahlenwirkung bei Glioblastomzellen.
Darmstadt, Technische Universität,
[Ph.D. Thesis]

Petraki, Chrysi Eirini (2014):
The role of the inhibitor of apoptosis protein Survivin in cellular radiation response.
Darmstadt, Technische Universität,
[Ph.D. Thesis]

Reul, Christian (2014):
Mechanisms and factors determining DSB repair pathway choice in G2.
Darmstadt, Technische Universität,
[Ph.D. Thesis]

2013

Beuke, Marcus (2013):
Untersuchung zur Relokalisierung heterochromatischer DNA Läsionen.
Darmstadt, Technische Universität,
[Ph.D. Thesis]

Dettmering, Till (2013):
Effects of carbon ion irradiation on inflammatory processes and normal tissue damage in the endothelium and the rat lung.
Darmstadt, Technische Universität,
[Ph.D. Thesis]

Ebel, Christian (2013):
Studien zur Reparatur Camptothecin- und Methylmethansulfonat-induzierter DNA-Schäden.
Darmstadt, Technische Universität,
[Ph.D. Thesis]

Frohns, Antonia (2013):
Untersuchung der DNA-Schadensantwort in der murinen Retina nach ionisierender Strahlung.
Darmstadt, Technische Universität,
[Ph.D. Thesis]

Helm, Alexander (2013):
Influence of High- and Low-LET Radiation on the Cardiac Differentiation of Mouse Embryonic Stem Cells.
Darmstadt, Technische Universität,
[Ph.D. Thesis]

Roth, Bastian (2013):
Exposure to sparsely and densely ionizing irradiation results in an immediate activation of K+ channels in A549 cells and in human peripheral blood lymphocytes.
Darmstadt, Technische Universität,
[Ph.D. Thesis]

2012

Reichert, Sebastian (2012):
Der Apoptoseinhibitor Survivin als molekulare Zielstruktur einer Modulation der intrinsischen Strahlenresistenz von Tumorzellen.
Darmstadt, Technische Universität,
[Ph.D. Thesis]

2011

Ensminger, Michael (2011):
Untersuchungen zur Reparatur Methylmethansulfonat-induzierter DNA-Schäden.
Darmstadt, Technische Universität,
[Ph.D. Thesis]

2010

Barton, Olivia (2010):
Checkpointkontrolle und Reparatur Heterochromatin-assoziierter DNA-Doppelstrangbrüche in bestrahlten G2-Phase Zellen.
Darmstadt, Technische Universität,
[Ph.D. Thesis]

Njoke A Biaka, Léopoldine Estelle (2010):
Der Beitrag des Nicht-Homologen End-Joining (NHEJ) bzw. der Homologen Rekombination (HR) zur Reparatur von strahleninduzierten DNA-Doppelstrangbrüchen (DSBs).
Technische Universität,
[Ph.D. Thesis]

Splinter, Jörn (2010):
Distribution and dynamics of charged particle-induced DNA double-strand breaks.
Darmstadt, Technische Universität,
[Ph.D. Thesis]

2009

Beucher, Andrea (2009):
Untersuchungen zur Reparatur von DNA-Doppelstrangbrüchen in der G2-Phase des Zellzyklus.
Darmstadt, Technische Universität,
[Ph.D. Thesis]

Grudzenski, Saskia (2009):
Einfluss von Kontrastmittel und der applizierten Röntgendosis auf die Induktion und Reparatur von DNA-Doppelstrangbrüchen.
Darmstadt, Technische Universität,
[Ph.D. Thesis]