Richter, Christian ; Hohmann, Katharina F. ; Toews, Sabrina ; Mathieu, Daniel ; Altincekic, Nadide ; Bains, Jasleen Kaur ; Binas, Oliver ; Ceylan, Betül ; Duchardt-Ferner, Elke ; Ferner, Jan ; Fürtig, Boris ; Grün, J. Tassilo ; Hengesbach, Martin ; Hymon, Daniel ; Jonker, Hendrik R. A. ; Knezic, Bozana ; Korn, Sophie M. ; Landgraf, Tom ; Löhr, Frank ; Peter, Stephen A. ; Pyper, Dennis J. ; Qureshi, Nusrat S. ; Schlundt, Andreas ; Schnieders, Robbin ; Stirnal, Elke ; Sudakov, Alexey ; Vögele, Jennifer ; Weigand, Julia E. ; Wirmer-Bartoschek, Julia ; Witt, Kerstin ; Wöhnert, Jens ; Schwalbe, Harald ; Wacker, Anna (2024)
¹H, ¹³C and ¹⁵N assignment of stem-loop SL1 from the 5'-UTR of SARS-CoV-2.
In: Biomolecular NMR Assignments, 2021, 15 (2)
doi: 10.26083/tuprints-00023514
Article, Secondary publication, Publisher's Version
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| Item Type: | Article |
|---|---|
| Type of entry: | Secondary publication |
| Title: | ¹H, ¹³C and ¹⁵N assignment of stem-loop SL1 from the 5'-UTR of SARS-CoV-2 |
| Language: | English |
| Date: | 30 September 2024 |
| Place of Publication: | Darmstadt |
| Year of primary publication: | 2021 |
| Place of primary publication: | Dordrecht |
| Publisher: | Springer Netherlands |
| Journal or Publication Title: | Biomolecular NMR Assignments |
| Volume of the journal: | 15 |
| Issue Number: | 2 |
| DOI: | 10.26083/tuprints-00023514 |
| Corresponding Links: | |
| Origin: | Secondary publication DeepGreen |
| Abstract: | The stem-loop (SL1) is the 5'-terminal structural element within the single-stranded SARS-CoV-2 RNA genome. It is formed by nucleotides 7–33 and consists of two short helical segments interrupted by an asymmetric internal loop. This architecture is conserved among Betacoronaviruses. SL1 is present in genomic SARS-CoV-2 RNA as well as in all subgenomic mRNA species produced by the virus during replication, thus representing a ubiquitous cis-regulatory RNA with potential functions at all stages of the viral life cycle. We present here the ¹H, ¹³C and ¹⁵N chemical shift assignment of the 29 nucleotides-RNA construct 5_SL1, which denotes the native 27mer SL1 stabilized by an additional terminal G-C base-pair. |
| Uncontrolled Keywords: | SARS-CoV-2, 5'-UTR, SL1, Solution NMR spectroscopy, COVID19-NMR |
| Status: | Publisher's Version |
| URN: | urn:nbn:de:tuda-tuprints-235142 |
| Classification DDC: | 500 Science and mathematics > 540 Chemistry 500 Science and mathematics > 570 Life sciences, biology |
| Divisions: | 10 Department of Biology > RNA Biochemistry |
| Date Deposited: | 30 Sep 2024 12:07 |
| Last Modified: | 05 Nov 2024 07:42 |
| SWORD Depositor: | Deep Green |
| URI: | https://tuprints.ulb.tu-darmstadt.de/id/eprint/23514 |
| PPN: | 523109121 |
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