Horst, Felix ; Schardt, Dieter ; Iwase, Hiroshi ; Schuy, Christoph ; Durante, Marco ; Weber, Uli (2024)
Physical characterization of ³He ion beams for radiotherapy and comparison with ⁴He.
In: Physics in Medicine & Biology, 2021, 66 (9)
doi: 10.26083/tuprints-00020501
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Item Type: | Article |
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Type of entry: | Secondary publication |
Title: | Physical characterization of ³He ion beams for radiotherapy and comparison with ⁴He |
Language: | English |
Date: | 5 March 2024 |
Place of Publication: | Darmstadt |
Year of primary publication: | 2021 |
Place of primary publication: | Bristol |
Publisher: | IOP Publishing |
Journal or Publication Title: | Physics in Medicine & Biology |
Volume of the journal: | 66 |
Issue Number: | 9 |
Collation: | 16 Seiten |
DOI: | 10.26083/tuprints-00020501 |
Corresponding Links: | |
Origin: | Secondary publication DeepGreen |
Abstract: | There is increasing interest in using helium ions for radiotherapy, complementary to protons and carbon ions. A large number of patients were treated with ⁴He ions in the US heavy ion therapy project and novel ⁴He ion treatment programs are under preparation, for instance in Germany and Japan. ³He ions have been proposed as an alternative to ⁴He ions because the acceleration of ³He is technically less difficult than ⁴He. In particular, beam contaminations have been pointed out as a potential safety issue for ⁴He ion beams. This motivated a series of experiments with ³He ion beams at Gesellschaft für Schwerionenforschung (GSI), Darmstadt. Measured ³He Bragg curves and fragmentation data in water are presented in this work. Those experimental data are compared with FLUKA Monte Carlo simulations. The physical characteristics of ³He ion beams are compared to those of ⁴He, for which a large set of data became available in recent years from the preparation work at the Heidelberger Ionenstrahl-Therapiezentrum (HIT). The dose distributions (spread out Bragg peaks, lateral profiles) that can be achieved with ³He ions are found to be competitive to ⁴He dose distributions. The effect of beam contaminations on ⁴He depth dose distribution is also addressed. It is concluded that ³He ions can be a viable alternative to ⁴He, especially for future compact therapy accelerator designs and upgrades of existing ion therapy facilities. |
Uncontrolled Keywords: | helium ion therapy, particle therapy, Bragg curve, nuclear fragmentation, heavy ion therapy, Monte Carlo simulation |
Status: | Publisher's Version |
URN: | urn:nbn:de:tuda-tuprints-205018 |
Classification DDC: | 500 Science and mathematics > 530 Physics 600 Technology, medicine, applied sciences > 610 Medicine and health |
Divisions: | 05 Department of Physics > Institute for Condensed Matter Physics |
Date Deposited: | 05 Mar 2024 12:55 |
Last Modified: | 28 May 2024 06:19 |
SWORD Depositor: | Deep Green |
URI: | https://tuprints.ulb.tu-darmstadt.de/id/eprint/20501 |
PPN: | 518625389 |
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