2024

Bogen, Jan P. ; Hinz, Steffen C. ; Grzeschik, Julius ; Ebenig, Aileen ; Krah, Simon ; Zielonka, Stefan ; Kolmar, Harald (2024)
Dual Function pH Responsive Bispecific Antibodies for Tumor Targeting and Antigen Depletion in Plasma.
In: Frontiers in Immunology, 2019, 10
doi: 10.26083/tuprints-00015735
Article, Secondary publication, Publisher's Version

Carrara, Stefania C. ; Bogen, Jan P. ; Fiebig, David ; Grzeschik, Julius ; Hock, Björn ; Kolmar, Harald (2024)
Targeted Phagocytosis Induction for Cancer Immunotherapy via Bispecific MerTK-Engaging Antibodies.
In: International Journal of Molecular Sciences, 2022, 23 (24)
doi: 10.26083/tuprints-00027673
Article, Secondary publication, Publisher's Version

Macarrón Palacios, Arturo ; Grzeschik, Julius ; Deweid, Lukas ; Krah, Simon ; Zielonka, Stefan ; Rösner, Thies ; Peipp, Matthias ; Valerius, Thomas ; Kolmar, Harald (2024)
Specific Targeting of Lymphoma Cells Using Semisynthetic Anti-Idiotype Shark Antibodies.
In: Frontiers in Immunology, 2020, 11
doi: 10.26083/tuprints-00017467
Article, Secondary publication, Publisher's Version

Elter, Adrian ; Bogen, Jan P. ; Hinz, Steffen C. ; Fiebig, David ; Macarrón Palacios, Arturo ; Grzeschik, Julius ; Hock, Björn ; Kolmar, Harald (2024)
Humanization of Chicken‐Derived scFv Using Yeast Surface Display and NGS Data Mining.
In: Biotechnology Journal : Systems & Synthetic Biology, Nanobiotech, Medicine, 2021, 16 (3)
doi: 10.26083/tuprints-00017792
Article, Secondary publication, Publisher's Version

Bogen, Jan P. ; Storka, Juliana ; Yanakieva, Desislava ; Fiebig, David ; Grzeschik, Julius ; Hock, Björn ; Kolmar, Harald (2024)
Isolation of Common Light Chain Antibodies from Immunized Chickens Using Yeast Biopanning and Fluorescence‐Activated Cell Sorting.
In: Biotechnology Journal : Systems and Synthetic Biology, Nanobiotech, Medicine, 2020, 16 (3)
doi: 10.26083/tuprints-00017449
Article, Secondary publication, Publisher's Version

Carrara, Stefania C. ; Fiebig, David ; Bogen, Jan P. ; Grzeschik, Julius ; Hock, Björn ; Kolmar, Harald (2024)
Recombinant Antibody Production Using a Dual-Promoter Single Plasmid System.
In: Antibodies, 2021, 10 (2)
doi: 10.26083/tuprints-00019564
Article, Secondary publication, Publisher's Version

2023

Bogen, Jan Patrick ; Carrara, Stefania Candela ; Fiebig, David ; Grzeschik, Julius ; Hock, Björn ; Kolmar, Harald (2023)
Supplemental Information with antibody sequences.
doi: 10.26083/tuprints-00017895
Data, Primary publication, Publisher's Version

Harwardt, Julia ; Carrara, Stefania C. ; Bogen, Jan P. ; Schoenfeld, Katrin ; Grzeschik, Julius ; Hock, Björn ; Kolmar, Harald (2023)
Generation of a symmetrical trispecific NK cell engager based on a two-in-one antibody.
In: Frontiers in Immunology, 2023, 14
doi: 10.26083/tuprints-00023673
Article, Secondary publication, Publisher's Version

2022

Carrara, Stefania C. ; Harwardt, Julia ; Grzeschik, Julius ; Hock, Björn ; Kolmar, Harald (2022)
TriTECM: A tetrafunctional T-cell engaging antibody with built-in risk mitigation of cytokine release syndrome.
In: Frontiers in Immunology, 2022, 13
doi: 10.26083/tuprints-00022942
Article, Secondary publication, Publisher's Version

Fiebig, David ; Bogen, Jan P. ; Carrara, Stefania C. ; Deweid, Lukas ; Zielonka, Stefan ; Grzeschik, Julius ; Hock, Björn ; Kolmar, Harald (2022)
Streamlining the Transition From Yeast Surface Display of Antibody Fragment Immune Libraries to the Production as IgG Format in Mammalian Cells.
In: Frontiers in Bioengineering and Biotechnology, 2022, 10
doi: 10.26083/tuprints-00021336
Article, Secondary publication, Publisher's Version

Harwardt, Julia ; Bogen, Jan P. ; Carrara, Stefania C. ; Ulitzka, Michael ; Grzeschik, Julius ; Hock, Björn ; Kolmar, Harald (2022)
A Generic Strategy to Generate Bifunctional Two-in-One Antibodies by Chicken Immunization.
In: Frontiers in Immunology, 2022, 13
doi: 10.26083/tuprints-00021242
Article, Secondary publication, Publisher's Version

2021

Bogen, Jan Patrick ; Grzeschik, Julius ; Jakobsen, Jørn ; Bähre, Alexandra ; Hock, Björn ; Kolmar, Harald (2021)
Treating Bladder Cancer: Engineering of Current and Next Generation Antibody-, Fusion Protein-, mRNA-, Cell- and Viral-Based Therapeutics.
In: Frontiers in Oncology, 2021, 11
doi: 10.26083/tuprints-00019435
Article, Secondary publication, Publisher's Version

Bogen, Jan P. ; Carrara, Stefania C. ; Fiebig, David ; Grzeschik, Julius ; Hock, Björn ; Kolmar, Harald (2021)
Design of a Trispecific Checkpoint Inhibitor and Natural Killer Cell Engager Based on a 2 + 1 Common Light Chain Antibody Architecture.
In: Frontiers in Immunology, 2021, 12
doi: 10.26083/tuprints-00019364
Article, Secondary publication, Publisher's Version

Bogen, Jan P. ; Carrara, Stefania C. ; Fiebig, David ; Grzeschik, Julius ; Hock, Björn ; Kolmar, Harald (2021)
Expeditious Generation of Biparatopic Common Light Chain Antibodies via Chicken Immunization and Yeast Display Screening.
In: Frontiers in Immunology, 2020, 11
doi: 10.26083/tuprints-00019264
Article, Secondary publication, Publisher's Version

2019

Grzeschik, Julius (2019)
Enabling technologies for the generation of high-affinity binders based on immunoglobulin scaffolds.
Technische Universität Darmstadt
Ph.D. Thesis, Primary publication

2017

Könning, Doreen ; Rhiel, Laura ; Empting, Martin ; Grzeschik, Julius ; Sellmann, Carolin ; Schröter, Christian ; Zielonka, Stefan ; Dickgießer, Stephan ; Pirzer, Thomas ; Yanakieva, Desislava ; Becker, Stefan ; Kolmar, Harald (2017)
Semi-synthetic vNAR libraries screened against therapeutic antibodies primarily deliver anti-idiotypic binders.
In: Scientific Reports, 2017, (1)
Article, Secondary publication, Publisher's Version