In building construction, sandwich panels are used for façade and roof cladding. In this case, large element lengths, which lead from a static point of view to multi-span systems, are preferred. The present work is about the load-bearing capacity under combination of bending and transverse compression, which usually occurs at intermediate supports of such continuous beams. Mechanically, this problem can be attributed to an elastically supported beam. The beam’s flexural stiffness corresponds to the stiffness of the face sheet in compression. The core specifies the size and type of elastic support. In the literature, several proposals for representing the support exist, from which the text presents, analyses and compares the approaches from Allen (1969), Stamm and Witte (1974), Baehre (1989), Kech (1991), Thermann (1989), Meyer (2000), Thomsen (1997), and Martikainen and Hassinen (1996). Based on the elastic support, the determination of the critical wrinkling stress is discussed and models for incorporating the stiffness of lightly profiled face sheets, namely Baehre (1989), Kech (1991), and Misiek and Hassinen (2010) are presented. With the background of this theoretical work, the thesis sets its focus on the load-bearing capacity under combined bending and transverse compression. For this purpose, both the testing of the strength (simulated central support test according to DIN EN 14509) and various calculation models (Berner 1995; Martikainen and Hassinen 1996; Meyer 2000; Lübke 2014) are described, discussed and interpreted. DIN EN 14509 leads to a fixed span in the simulated central support test. An extensive parametric study disproves this pre-condition. The experiments of this thesis demonstrate amongst others the relevance of a realistically determined span in the simulated central support test and proof that the simulated central support test is able to replace a two-span test. Comparative numerical studies confirm the test results. The experiments of this thesis are combined with several tests for the German approval and the CE-marking. Their evaluation shows the limits of the existing calculation models. Finally, a new calculation model based on the FE method is presented, with which the load-bearing capacity under bending and transverse compression can be well predicted.