Velasquez, Sara T. R. ; Jang, Daseul ; Jenkins, Peter ; Liu, Peng ; Yang, Liu ; Korley, LaShanda T. J. ; Bruns, Nico (2024)
Peptide‐Reinforced Amphiphilic Polymer Conetworks.
In: Advanced Functional Materials, 2022, 32 (51)
doi: 10.26083/tuprints-00023688
Article, Secondary publication, Publisher's Version
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Item Type: | Article |
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Type of entry: | Secondary publication |
Title: | Peptide‐Reinforced Amphiphilic Polymer Conetworks |
Language: | English |
Date: | 22 January 2024 |
Place of Publication: | Darmstadt |
Year of primary publication: | 2022 |
Place of primary publication: | Weinheim |
Publisher: | Wiley-VCH |
Journal or Publication Title: | Advanced Functional Materials |
Volume of the journal: | 32 |
Issue Number: | 51 |
Collation: | 15 Seiten |
DOI: | 10.26083/tuprints-00023688 |
Corresponding Links: | |
Origin: | Secondary publication DeepGreen |
Abstract: | Amphiphilic polymer conetworks (APCNs) are polymer networks composed of hydrophilic and hydrophobic chain segments. Their applications range from soft contact lenses to membranes and biomaterials. APCNs based on polydimethylsiloxane (PDMS) and poly(2‐hydroxyethyl acrylate) are flexible and elastic in the dry and swollen state. However, they are not good at resisting deformation under load, i.e., their toughness is low. A bio‐inspired approach to reinforce APCNs is presented based on the incorporation of poly(β‐benzyl‐L‐aspartate) (PBLA) blocks between cross‐linking points and PDMS chain segments. The mechanical properties of the resulting peptide‐reinforced APCNs can be tailored by the secondary structure of the peptide chains (β‐sheets or a mixture of α‐helices and β‐sheets). Compared to non‐reinforced APCNs, the peptide‐reinforced networks have higher extensibility (53 vs. up to 341%), strength (0.71 ± 0.16 vs. 22.28 ± 2.81 MPa), and toughness (0.10 ± 0.04 vs. up to 4.85 ± 1.32 MJ m⁻³), as measured in their dry state. The PBLA peptides reversibly toughen and reinforce the APCNs, while other key material properties of APCNs are retained, such as optical transparency and swellability in water and organic solvents. This paves the way for applications of APCNs that benefit from significantly increased mechanical properties. |
Uncontrolled Keywords: | amphiphilic polymer networks, bio‐inspired polymeric materials, hydrogels, mechanical properties, peptide‐polymer hybrids, peptides, polymer reinforcements |
Identification Number: | 2207317 |
Status: | Publisher's Version |
URN: | urn:nbn:de:tuda-tuprints-236881 |
Classification DDC: | 500 Science and mathematics > 540 Chemistry 600 Technology, medicine, applied sciences > 660 Chemical engineering |
Divisions: | Interdisziplinäre Forschungsprojekte > Centre for Synthetic Biology 07 Department of Chemistry > Ernst-Berl-Institut > Fachgebiet Makromolekulare Chemie |
Date Deposited: | 22 Jan 2024 13:50 |
Last Modified: | 24 Jan 2024 08:31 |
SWORD Depositor: | Deep Green |
URI: | https://tuprints.ulb.tu-darmstadt.de/id/eprint/23688 |
PPN: | 514919477 |
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