Böttcher, Adriana ; Zarucha, Alexis ; Köbe, Theresa ; Gaubert, Malo ; Höppner, Angela ; Altenstein, Slawek ; Bartels, Claudia ; Buerger, Katharina ; Dechent, Peter ; Dobisch, Laura ; Ewers, Michael ; Fliessbach, Klaus ; Freiesleben, Silka Dawn ; Frommann, Ingo ; Haynes, John Dylan ; Janowitz, Daniel ; Kilimann, Ingo ; Kleineidam, Luca ; Laske, Christoph ; Maier, Franziska ; Metzger, Coraline ; Munk, Matthias H. J. ; Perneczky, Robert ; Peters, Oliver ; Priller, Josef ; Rauchmann, Boris-Stephan ; Roy, Nina ; Scheffler, Klaus ; Schneider, Anja ; Spottke, Annika ; Teipel, Stefan J. ; Wiltfang, Jens ; Wolfsgruber, Steffen ; Yakupov, Renat ; Düzel, Emrah ; Jessen, Frank ; Röske, Sandra ; Wagner, Michael ; Kempermann, Gerd ; Wirth, Miranka (2022)
Musical Activity During Life Is Associated With Multi-Domain Cognitive and Brain Benefits in Older Adults.
In: Frontiers in Psychology, 2022, 13
doi: 10.26083/tuprints-00022341
Article, Secondary publication, Publisher's Version
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Item Type: | Article |
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Type of entry: | Secondary publication |
Title: | Musical Activity During Life Is Associated With Multi-Domain Cognitive and Brain Benefits in Older Adults |
Language: | English |
Date: | 12 September 2022 |
Place of Publication: | Darmstadt |
Year of primary publication: | 2022 |
Publisher: | Frontiers Media S.A. |
Journal or Publication Title: | Frontiers in Psychology |
Volume of the journal: | 13 |
Collation: | 16 Seiten |
DOI: | 10.26083/tuprints-00022341 |
Corresponding Links: | |
Origin: | Secondary publication DeepGreen |
Abstract: | Regular musical activity as a complex multimodal lifestyle activity is proposed to be protective against age-related cognitive decline and Alzheimer’s disease. This cross-sectional study investigated the association and interplay between musical instrument playing during life, multi-domain cognitive abilities and brain morphology in older adults (OA) from the DZNE-Longitudinal Cognitive Impairment and Dementia Study (DELCODE) study. Participants reporting having played a musical instrument across three life periods (n = 70) were compared to controls without a history of musical instrument playing (n = 70), well-matched for reserve proxies of education, intelligence, socioeconomic status and physical activity. Participants with musical activity outperformed controls in global cognition, working memory, executive functions, language, and visuospatial abilities, with no effects seen for learning and memory. The musically active group had greater gray matter volume in the somatosensory area, but did not differ from controls in higher-order frontal, temporal, or hippocampal volumes. However, the association between gray matter volume in distributed frontal-to-temporal regions and cognitive abilities was enhanced in participants with musical activity compared to controls. We show that playing a musical instrument during life relates to better late-life cognitive abilities and greater brain capacities in OA. Musical activity may serve as a multimodal enrichment strategy that could help preserve cognitive and brain health in late life. Longitudinal and interventional studies are needed to support this notion. |
Uncontrolled Keywords: | brain aging, resilience, cognitive reserve, prevention, brain plasticity, instrument playing |
Status: | Publisher's Version |
URN: | urn:nbn:de:tuda-tuprints-223415 |
Classification DDC: | 100 Philosophy and psychology > 150 Psychology 600 Technology, medicine, applied sciences > 610 Medicine and health |
Divisions: | 10 Department of Biology > Systems Neurophysiology |
Date Deposited: | 12 Sep 2022 13:05 |
Last Modified: | 14 Nov 2023 19:05 |
SWORD Depositor: | Deep Green |
URI: | https://tuprints.ulb.tu-darmstadt.de/id/eprint/22341 |
PPN: | 499511786 |
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