Schmidt, Annika ; Zhang, Hui ; Cardoso, M. Cristina (2020)
MeCP2 and Chromatin Compartmentalization.
In: Cells, 2020, 9 (4)
doi: 10.25534/tuprints-00013360
Article, Secondary publication, Publisher's Version
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cells-09-00878-v2.pdf Copyright Information: CC BY 4.0 International - Creative Commons, Attribution. Download (1MB) | Preview |
| Item Type: | Article |
|---|---|
| Type of entry: | Secondary publication |
| Title: | MeCP2 and Chromatin Compartmentalization |
| Language: | English |
| Date: | 25 August 2020 |
| Place of Publication: | Darmstadt |
| Year of primary publication: | 2020 |
| Publisher: | MDPI |
| Journal or Publication Title: | Cells |
| Volume of the journal: | 9 |
| Issue Number: | 4 |
| DOI: | 10.25534/tuprints-00013360 |
| Corresponding Links: | |
| Origin: | Secondary publication via sponsored Golden Open Access |
| Abstract: | Methyl-CpG binding protein 2 (MeCP2) is a multifunctional epigenetic reader playing a role in transcriptional regulation and chromatin structure, which was linked to Rett syndrome in humans. Here, we focus on its isoforms and functional domains, interactions, modifications and mutations found in Rett patients. Finally, we address how these properties regulate and mediate the ability of MeCP2 to orchestrate chromatin compartmentalization and higher order genome architecture. |
| Status: | Publisher's Version |
| URN: | urn:nbn:de:tuda-tuprints-133604 |
| Classification DDC: | 500 Science and mathematics > 570 Life sciences, biology |
| Divisions: | 10 Department of Biology > Cell Biology and Epigenetics |
| Date Deposited: | 25 Aug 2020 09:22 |
| Last Modified: | 25 Nov 2024 10:01 |
| URI: | https://tuprints.ulb.tu-darmstadt.de/id/eprint/13360 |
| PPN: | 468216413 |
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