Uth, Christina ; Englert, Simon ; Avrutina, Olga ; Kolmar, Harald ; Knauer, Sascha (2024)
Novel amino‐Li resin for water‐based solid‐phase peptide synthesis.
In: Journal of Peptide Science, 2023, 29 (12)
doi: 10.26083/tuprints-00027214
Article, Secondary publication, Publisher's Version
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| Item Type: | Article |
|---|---|
| Type of entry: | Secondary publication |
| Title: | Novel amino‐Li resin for water‐based solid‐phase peptide synthesis |
| Language: | English |
| Date: | 28 May 2024 |
| Place of Publication: | Darmstadt |
| Year of primary publication: | December 2023 |
| Place of primary publication: | New York |
| Publisher: | John Wiley & Sons |
| Journal or Publication Title: | Journal of Peptide Science |
| Volume of the journal: | 29 |
| Issue Number: | 12 |
| Collation: | 7 Seiten |
| DOI: | 10.26083/tuprints-00027214 |
| Corresponding Links: | |
| Origin: | Secondary publication DeepGreen |
| Abstract: | We report the first application of a novel amino‐Li resin to water‐based solid‐phase peptide synthesis (SPPS) applying the Smoc‐protecting group approach. We demonstrated that it is a suitable support for the sustainable water‐based alternative to a classical SPPS approach. The resin possesses good swelling properties in aqueous milieu, provides significant coupling sites, and may be applicable to the synthesis of difficult sequences and aggregation‐prone peptides. |
| Uncontrolled Keywords: | ASPPS, Smoc strategy, solid support, sustainable peptide synthesis, water‐based peptide synthesis |
| Identification Number: | Artikel-ID: e3527 |
| Status: | Publisher's Version |
| URN: | urn:nbn:de:tuda-tuprints-272142 |
| Additional Information: | Dedicated to the memory of Michael Przybylski. |
| Classification DDC: | 500 Science and mathematics > 540 Chemistry 500 Science and mathematics > 570 Life sciences, biology |
| Divisions: | 07 Department of Chemistry > Clemens-Schöpf-Institut > Fachgebiet Biochemie |
| Date Deposited: | 28 May 2024 11:49 |
| Last Modified: | 18 Sep 2024 06:24 |
| SWORD Depositor: | Deep Green |
| URI: | https://tuprints.ulb.tu-darmstadt.de/id/eprint/27214 |
| PPN: | 521531268 |
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