2024

Buffa, Vanessa ; Meyners, Christian ; Sugiarto, Wisely Oki ; Bauder, Michael ; Gaali, Steffen ; Hausch, Felix (2024)
1,4‐Pyrazolyl‐Containing SAFit‐Analogues are Selective FKBP51 Inhibitors With Improved Ligand Efficiency and Drug‐Like Profile.
In: ChemMedChem, 2024, 19 (17)
doi: 10.26083/tuprints-00028297
Article, Secondary publication, Publisher's Version

Krajczy, Patryk ; Meyners, Christian ; Repity, Maximilian L. ; Hausch, Felix (2024)
Structure‐Based Design of Ultrapotent Tricyclic Ligands for FK506‐Binding Proteins.
In: Chemistry – A European Journal, 2024, 30 (45)
doi: 10.26083/tuprints-00028291
Article, Secondary publication, Publisher's Version

Jagtap, Pravin Kumar Ankush ; Kubelka, Tomáš ; Soni, Komal ; Will, Cindy L. ; Garg, Divita ; Sippel, Claudia ; Kapp, Tobias G. ; Potukuchi, Harish Kumar ; Schorpp, Kenji ; Hadian, Kamyar ; Kessler, Horst ; Lührmann, Reinhard ; Hausch, Felix ; Bach, Thorsten ; Sattler, Michael (2024)
Identification of phenothiazine derivatives as UHM-binding inhibitors of early spliceosome assembly.
In: Nature Communications, 2020, 11 (1)
doi: 10.26083/tuprints-00023981
Article, Secondary publication, Publisher's Version

Martinelli, Silvia ; Anderzhanova, Elmira A. ; Bajaj, Thomas ; Wiechmann, Svenja ; Dethloff, Frederik ; Weckmann, Katja ; Heinz, Daniel E. ; Ebert, Tim ; Hartmann, Jakob ; Geiger, Thomas M. ; Döngi, Michael ; Hafner, Kathrin ; Pöhlmann, Max L. ; Jollans, Lee ; Philipsen, Alexandra ; Schmidt, Susanne V. ; Schmidt, Ulrike ; Maccarrone, Giuseppina ; Stein, Valentin ; Hausch, Felix ; Turck, Christoph W. ; Schmidt, Mathias V. ; Gellner, Anne-Kathrin ; Kuster, Bernhard ; Gassen, Nils C. (2024)
Stress-primed secretory autophagy promotes extracellular BDNF maturation by enhancing MMP9 secretion.
In: Nature Communications, 2021, 12 (1)
doi: 10.26083/tuprints-00023586
Article, Secondary publication, Publisher's Version

Deutscher, Robin C. E. ; Karagöz, Mustafa Safa ; Purder, Patrick L. ; Kolos, Jürgen M. ; Meyners, Christian ; Oki Sugiarto, Wisely ; Krajczy, Patryk ; Tebbe, Frederike ; Geiger, Thomas M. ; Ünal, Can ; Hellmich, Ute A. ; Steinert, Michael ; Hausch, Felix (2024)
[4.3.1]Bicyclic FKBP Ligands Inhibit Legionella Pneumophila Infection by LpMip‐Dependent and LpMip‐Independent Mechanisms.
In: ChemBioChem, 2023, 24 (21)
doi: 10.26083/tuprints-00027244
Article, Secondary publication, Publisher's Version

Geiger, Thomas M. ; Walz, Michael ; Meyners, Christian ; Kuehn, Angela ; Dreizler, Johannes K. ; Sugiarto, Wisely O. ; Maciel, Edvaldo V. S. ; Zheng, Min ; Lermyte, Frederik ; Hausch, Felix (2024)
Discovery of a Potent Proteolysis Targeting Chimera Enables Targeting the Scaffolding Functions of FK506‐Binding Protein 51 (FKBP51).
In: Angewandte Chemie International Edition, 2024, 63 (3)
doi: 10.26083/tuprints-00027257
Article, Secondary publication, Publisher's Version

Schraut, Karla‐Gerlinde ; Kalnytska, Oleksandra ; Lamp, Daniel ; Jastroch, Martin ; Eder, Matthias ; Hausch, Felix ; Gassen, Nils C. ; Moore, Sarah ; Nagaraj, Nagarjuna ; Lopez, Juan P. ; Chen, Alon ; Schmidt, Mathias V. (2024)
Loss of the psychiatric risk factor SLC6A15 is associated with increased metabolic functions in primary hippocampal neurons.
In: European Journal of Neuroscience, 2020, 53 (2)
doi: 10.26083/tuprints-00016168
Article, Secondary publication, Publisher's Version

Bischoff, Matthias ; Mayer, Peter ; Meyners, Christian ; Hausch, Felix (2024)
Enantioselective Synthesis of a Tricyclic, sp³‐Rich Diazatetradecanedione: an Amino Acid‐Based Natural Product‐Like Scaffold.
In: Chemistry – A European Journal, 2020, 26 (21)
doi: 10.26083/tuprints-00015975
Article, Secondary publication, Publisher's Version

Hähle, Andreas ; Merz, Stephanie ; Meyners, Christian ; Hausch, Felix (2024)
The Many Faces of FKBP51.
In: Biomolecules, 2019, 9 (1)
doi: 10.26083/tuprints-00016874
Article, Secondary publication, Publisher's Version

2022

Purder, Patrick L. ; Meyners, Christian ; Krysenko, Sergii ; Funk, Jonathan ; Wohlleben, Wolfgang ; Hausch, Felix (2022)
Mechanism‐Based Design of the First GlnA4‐Specific Inhibitors.
In: ChemBioChem, 2022, 23 (19)
doi: 10.26083/tuprints-00022898
Article, Secondary publication, Publisher's Version

Lerma Romero, Jorge A. ; Meyners, Christian ; Christmann, Andreas ; Reinbold, Lisa M. ; Charalampidou, Anna ; Hausch, Felix ; Kolmar, Harald (2022)
Binding pocket stabilization by high-throughput screening of yeast display libraries.
In: Frontiers in Molecular Biosciences, 2022, 9
doi: 10.26083/tuprints-00022911
Article, Secondary publication, Publisher's Version

Wedel, Saskia ; Hahnefeld, Lisa ; Alnouri, Mohamad Wessam ; Offermanns, Stefan ; Hausch, Felix ; Geisslinger, Gerd ; Sisignano, Marco (2022)
The FKBP51 Inhibitor SAFit2 Restores the Pain-Relieving C16 Dihydroceramide after Nerve Injury.
In: International Journal of Molecular Sciences, 2022, 23 (22)
doi: 10.26083/tuprints-00022974
Article, Secondary publication, Publisher's Version

Berthold, Emilia J. ; Ma-Lauer, Yue ; Chakraborty, Ashesh ; Brunn, Brigitte von ; Hilgendorff, Anne ; Hatz, Rudolf ; Behr, Jürgen ; Hausch, Felix ; Staab-Weijnitz, Claudia A. ; Brunn, Albrecht von (2022)
Effects of immunophilin inhibitors and non-immunosuppressive analogs on coronavirus replication in human infection models.
In: Frontiers in Cellular and Infection Microbiology, 2022, 12
doi: 10.26083/tuprints-00022480
Article, Secondary publication, Publisher's Version

Nehls, Thomas ; Heymann, Tim ; Meyners, Christian ; Hausch, Felix ; Lermyte, Frederik (2022)
Fenton-Chemistry-Based Oxidative Modification of Proteins Reflects Their Conformation.
In: International Journal of Molecular Sciences, 2022, 22 (18)
doi: 10.26083/tuprints-00021257
Article, Secondary publication, Publisher's Version

2019

Kolos, Jürgen M. ; Voll, Andreas M. ; Bauder, Michael ; Hausch, Felix (2019)
FKBP Ligands—Where We Are and Where to Go?
In: Frontiers in Pharmacology, 2018, 9
Article, Secondary publication, Publisher's Version

Geiger, Thomas M. ; Hähle, Andreas ; Merz, Stephanie ; Meyners, Christian ; Tianqi, Mao ; Kolos, Jürgen ; Hausch, Felix (2019)
FKBP51 and FKBP12.6—Novel and tight interactors of Glomulin.
In: PLOS ONE, 2019, 14 (9)
Article, Secondary publication, Publisher's Version