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Das FuN Screen-Prinzip zur experimentellen Analyse von Nanoporen in E. coli

Weber, Wadim ; Probanowski, Tobias ; Eisenhauer, Klara ; Kemp, Philipp ; Stein, Viktor (2025)
Das FuN Screen-Prinzip zur experimentellen Analyse von Nanoporen in E. coli.
In: BIOspektrum : Das Magazin für Biowissenschaften, 2023, 29 (3)
doi: 10.26083/tuprints-00028369
Article, Secondary publication, Publisher's Version

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Item Type: Article
Type of entry: Secondary publication
Title: Das FuN Screen-Prinzip zur experimentellen Analyse von Nanoporen in E. coli
Language: German
Date: 16 January 2025
Place of Publication: Darmstadt
Year of primary publication: May 2023
Place of primary publication: Berlin ; Heidelberg
Publisher: Springer
Journal or Publication Title: BIOspektrum : Das Magazin für Biowissenschaften
Volume of the journal: 29
Issue Number: 3
DOI: 10.26083/tuprints-00028369
Corresponding Links:
Origin: Secondary publication DeepGreen
Abstract:

Nanopores constitute an important class of biotechnologically relevant proteins. Unlike binders and enzymes, their experimental characterization is limited to high-resolution, yet low throughput biophysical methods. Addressing this technological gap, the functional nanopore (FuN) screen now provides a versatile assay to study and engineer nanopores in Escherichia coli combining quantitative resolution with the ease, scalability, and throughput of cellular assays.

Uncontrolled Keywords: Life Sciences, general, Biochemistry, general, Human Genetics, Microbiology, Pharmacology/Toxicology
Status: Publisher's Version
URN: urn:nbn:de:tuda-tuprints-283696
Classification DDC: 500 Science and mathematics > 570 Life sciences, biology
Divisions: 10 Department of Biology > Protein Engineering of Ion Conducting Nanopores
Interdisziplinäre Forschungsprojekte > Centre for Synthetic Biology
Date Deposited: 16 Jan 2025 13:52
Last Modified: 16 Jan 2025 13:53
SWORD Depositor: Deep Green
URI: https://tuprints.ulb.tu-darmstadt.de/id/eprint/28369
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