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Nanostructured Ti-13Nb-13Zr alloy for implant application — material scientific, technological, and biological aspects

Klinge, Lina ; Kluy, Lukas ; Spiegel, Christopher ; Siemers, Carsten ; Groche, Peter ; Coraça-Huber, Débora (2023)
Nanostructured Ti-13Nb-13Zr alloy for implant application — material scientific, technological, and biological aspects.
In: Frontiers in Bioengineering and Biotechnology, 2023, 11
doi: 10.26083/tuprints-00024504
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Item Type: Article
Type of entry: Secondary publication
Title: Nanostructured Ti-13Nb-13Zr alloy for implant application — material scientific, technological, and biological aspects
Language: English
Date: 11 September 2023
Place of Publication: Darmstadt
Year of primary publication: 2023
Publisher: Frontiers Media S.A.
Journal or Publication Title: Frontiers in Bioengineering and Biotechnology
Volume of the journal: 11
Collation: 15 Seiten
DOI: 10.26083/tuprints-00024504
Corresponding Links:
Origin: Secondary publication DeepGreen

In dentistry, the most commonly used implant materials are CP-Titanium Grade 4 and Ti-6Al-4V ELI, possessing comparably high Young’s modulus (>100 GPa). In the present study, the second-generation titanium alloy Ti-13Nb-13Zr is investigated with respect to the production of advanced dental implant systems. This should be achieved by the fabrication of long semi-finished bars with high strength and sufficient ductility to allow the automated production of small implants at low Young’s modulus (<80 GPa) to minimize stress shielding, bone resorption, and gap formation between the bone and implant. In addition, bacterial colonization is to be reduced, and bone adhesion is to be enhanced by adjusting the microstructure. To do so, a dedicated thermo-mechanical treatment for Ti-13Nb-13Zr has been developed. This includes the adaption of equal channel angular swaging, a modern process of severe plastic deformation to continuously manufacture nanostructured materials, to Ti-13Nb-13Zr and short-time recrystallization and ageing treatments. In particular, two-pass equal channel angular swaging at a deformation temperature of 150°C and a counterpressure of 8 MPa has successfully been used to avoid shear band formation during deformation and to produce long Ti-13Nb-13Zr bars of 8 mm diameter. During recrystallization treatment at 700°C for 10 min followed by water quenching, a sub-micron-size primary α-phase in a matrix of α″-phase was developed. Subsequent ageing at 500°C for 1 h leads to martensite decomposition and, thus, to a homogeneously nanostructured microstructure of α- and β-phase with substructures smaller than 200 nm. The resulting mechanical properties, especially the ultimate tensile strength of more than 990 MPa, fulfill the requirements of ASTM F1713 at Young’s modulus of 73 GPa. Biological investigations show promising results in reducing bacterial biofilm formation and increased cell proliferation of osteoblasts compared to CP-Titanium Grade 4 and Ti-6Al-4V ELI, especially, if etched surfaces are applied.

Uncontrolled Keywords: Ti-13Nb-13Zr, nanostructured titanium, equal channel angular swaging, biofilm, Staphylococcus aureus , implant material, osteoblasts
Status: Publisher's Version
URN: urn:nbn:de:tuda-tuprints-245041
Classification DDC: 500 Science and mathematics > 540 Chemistry
500 Science and mathematics > 570 Life sciences, biology
600 Technology, medicine, applied sciences > 620 Engineering and machine engineering
Divisions: 16 Department of Mechanical Engineering > Institut für Produktionstechnik und Umformmaschinen (PtU)
Date Deposited: 11 Sep 2023 12:08
Last Modified: 31 Oct 2023 12:56
SWORD Depositor: Deep Green
URI: https://tuprints.ulb.tu-darmstadt.de/id/eprint/24504
PPN: 512774145
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