TU Darmstadt / ULB / TUprints

Vom Huhn abgeleitete Antikörper für Diagnostik und Immuntherapie

Elter, Adrian ; Bogen, Jan P. ; Habermann, Jan ; Kolmar, Harald (2024)
Vom Huhn abgeleitete Antikörper für Diagnostik und Immuntherapie.
In: BIOspektrum : Das Magazin für Biowissenschaften, 2021, 27 (5)
doi: 10.26083/tuprints-00023545
Article, Secondary publication, Publisher's Version

[img] Text
Copyright Information: CC BY 4.0 International - Creative Commons, Attribution.

Download (628kB)
Item Type: Article
Type of entry: Secondary publication
Title: Vom Huhn abgeleitete Antikörper für Diagnostik und Immuntherapie
Language: German
Date: 30 April 2024
Place of Publication: Darmstadt
Year of primary publication: September 2021
Place of primary publication: Berlin ; Heidelberg
Publisher: Springer
Journal or Publication Title: BIOspektrum : Das Magazin für Biowissenschaften
Volume of the journal: 27
Issue Number: 5
DOI: 10.26083/tuprints-00023545
Corresponding Links:
Origin: Secondary publication DeepGreen

Due to the large evolutionary distance between birds (Aves) und humans, immunization of chickens with human proteins results in a strong response of the bird’s adaptive immune system to proteins of mammalian origin. Additionally, chicken-derived antibodies display less undesired cross-reactivity in analytical setups than conventional rodent-derived antibodies. Due to these features as well as the facile amplification of antibody-coding genes, chicken-derived antibodies emerged as promising molecules for the immunotherapy and various biotechnological applications.

Uncontrolled Keywords: Life Sciences, general, Biochemistry, general, Human Genetics, Microbiology, Pharmacology/Toxicology
Status: Publisher's Version
URN: urn:nbn:de:tuda-tuprints-235454
Classification DDC: 500 Science and mathematics > 540 Chemistry
500 Science and mathematics > 570 Life sciences, biology
600 Technology, medicine, applied sciences > 610 Medicine and health
Divisions: 07 Department of Chemistry > Clemens-Schöpf-Institut > Fachgebiet Biochemie
Date Deposited: 30 Apr 2024 09:10
Last Modified: 30 Apr 2024 09:11
SWORD Depositor: Deep Green
URI: https://tuprints.ulb.tu-darmstadt.de/id/eprint/23545
Actions (login required)
View Item View Item