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Considerations for Upright Particle Therapy Patient Positioning and Associated Image Guidance

Volz, Lennart ; Sheng, Yinxiangzi ; Durante, Marco ; Graeff, Christian (2022):
Considerations for Upright Particle Therapy Patient Positioning and Associated Image Guidance. (Publisher's Version)
In: Frontiers in Oncology, 12, Frontiers Media S.A., e-ISSN 2234-943X,
DOI: 10.26083/tuprints-00022017,
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Item Type: Article
Origin: Secondary publication DeepGreen
Status: Publisher's Version
Title: Considerations for Upright Particle Therapy Patient Positioning and Associated Image Guidance
Language: English
Abstract:

Particle therapy is a rapidly growing field in cancer therapy. Worldwide, over 100 centers are in operation, and more are currently in construction phase. The interest in particle therapy is founded in the superior target dose conformity and healthy tissue sparing achievable through the particles’ inverse depth dose profile. This physical advantage is, however, opposed by increased complexity and cost of particle therapy facilities. Particle therapy, especially with heavier ions, requires large and costly equipment to accelerate the particles to the desired treatment energy and steer the beam to the patient. A significant portion of the cost for a treatment facility is attributed to the gantry, used to enable different beam angles around the patient for optimal healthy tissue sparing. Instead of a gantry, a rotating chair positioning system paired with a fixed horizontal beam line presents a suitable cost-efficient alternative. Chair systems have been used already at the advent of particle therapy, but were soon dismissed due to increased setup uncertainty associated with the upright position stemming from the lack of dedicated image guidance systems. Recently, treatment chairs gained renewed interest due to the improvement in beam delivery, commercial availability of vertical patient CT imaging and improved image guidance systems to mitigate the problem of anatomical motion in seated treatments. In this review, economical and clinical reasons for an upright patient positioning system are discussed. Existing designs targeted for particle therapy are reviewed, and conclusions are drawn on the design and construction of chair systems and associated image guidance. Finally, the different aspects from literature are channeled into recommendations for potential upright treatment layouts, both for retrofitting and new facilities.

Journal or Publication Title: Frontiers in Oncology
Volume of the journal: 12
Place of Publication: Darmstadt
Publisher: Frontiers Media S.A.
Collation: 13 Seiten
Uncontrolled Keywords: upright CT, upright treatment, particle therapy, image guidance, seated treatment, treatment chair
Classification DDC: 500 Naturwissenschaften und Mathematik > 530 Physik
600 Technik, Medizin, angewandte Wissenschaften > 620 Ingenieurwissenschaften
Divisions: 18 Department of Electrical Engineering and Information Technology > Technik der Strahlentherapie
05 Department of Physics > Institute for Condensed Matter Physics
Date Deposited: 19 Oct 2022 12:46
Last Modified: 25 Oct 2022 07:13
DOI: 10.26083/tuprints-00022017
Corresponding Links:
URN: urn:nbn:de:tuda-tuprints-220172
SWORD Depositor: Deep Green
URI: https://tuprints.ulb.tu-darmstadt.de/id/eprint/22017
PPN: 500721475
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