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A journey through the microscopic ages of DNA replication

Reinhart, Marius Armin ; Cardoso, M. Cristina (2022):
A journey through the microscopic ages of DNA replication. (Publisher's Version)
In: Protoplasma, 254 (3), pp. 1151-1162. Springer, ISSN 0033-183X, e-ISSN 1615-6102,
DOI: 10.26083/tuprints-00013357,
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Item Type: Article
Origin: Secondary publication
Status: Publisher's Version
Title: A journey through the microscopic ages of DNA replication
Language: English
Abstract:

Scientific discoveries and technological advancements are inseparable but not always take place in a coherent chronological manner. In the next, we will provide a seemingly unconnected and serendipitous series of scientific facts that, in the whole, converged to unveil DNA and its duplication. We will not cover here the many and fundamental contributions from microbial genetics and in vitro biochemistry. Rather, in this journey, we will emphasize the interplay between microscopy development culminating on super resolution fluorescence microscopy (i.e., nanoscopy) and digital image analysis and its impact on our understanding of DNA duplication. We will interlace the journey with landmark concepts and experiments that have brought the cellular DNA replication field to its present state.

Journal or Publication Title: Protoplasma
Volume of the journal: 254
Issue Number: 3
Publisher: Springer
Classification DDC: 500 Naturwissenschaften und Mathematik > 570 Biowissenschaften, Biologie
600 Technik, Medizin, angewandte Wissenschaften > 610 Medizin, Gesundheit
Divisions: 10 Department of Biology > Cell Biology and Epigenetics
Date Deposited: 07 Mar 2022 13:38
Last Modified: 10 Mar 2022 09:51
DOI: 10.26083/tuprints-00013357
Corresponding Links:
URN: urn:nbn:de:tuda-tuprints-133579
URI: https://tuprints.ulb.tu-darmstadt.de/id/eprint/13357
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