Reinhart, Marius Armin ; Cardoso, M. Cristina (2022):
A journey through the microscopic ages of DNA replication. (Publisher's Version)
In: Protoplasma, 254 (3), pp. 1151-1162. Springer, ISSN 0033-183X, e-ISSN 1615-6102,
DOI: 10.26083/tuprints-00013357,
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| Item Type: | Article |
|---|---|
| Origin: | Secondary publication |
| Status: | Publisher's Version |
| Title: | A journey through the microscopic ages of DNA replication |
| Language: | English |
| Abstract: | Scientific discoveries and technological advancements are inseparable but not always take place in a coherent chronological manner. In the next, we will provide a seemingly unconnected and serendipitous series of scientific facts that, in the whole, converged to unveil DNA and its duplication. We will not cover here the many and fundamental contributions from microbial genetics and in vitro biochemistry. Rather, in this journey, we will emphasize the interplay between microscopy development culminating on super resolution fluorescence microscopy (i.e., nanoscopy) and digital image analysis and its impact on our understanding of DNA duplication. We will interlace the journey with landmark concepts and experiments that have brought the cellular DNA replication field to its present state. |
| Journal or Publication Title: | Protoplasma |
| Volume of the journal: | 254 |
| Issue Number: | 3 |
| Place of Publication: | Darmstadt |
| Publisher: | Springer |
| Classification DDC: | 500 Naturwissenschaften und Mathematik > 570 Biowissenschaften, Biologie 600 Technik, Medizin, angewandte Wissenschaften > 610 Medizin, Gesundheit |
| Divisions: | 10 Department of Biology > Cell Biology and Epigenetics |
| Date Deposited: | 07 Mar 2022 13:38 |
| Last Modified: | 03 Mar 2023 09:45 |
| DOI: | 10.26083/tuprints-00013357 |
| Corresponding Links: | |
| URN: | urn:nbn:de:tuda-tuprints-133579 |
| URI: | https://tuprints.ulb.tu-darmstadt.de/id/eprint/13357 |
| PPN: | 505407647 |
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