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A journey through the microscopic ages of DNA replication

Reinhart, Marius Armin ; Cardoso, M. Cristina (2022)
A journey through the microscopic ages of DNA replication.
In: Protoplasma, 2016, 254 (3)
doi: 10.26083/tuprints-00013357
Article, Secondary publication, Publisher's Version

Copyright Information: CC BY 4.0 International - Creative Commons, Attribution.

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Item Type: Article
Type of entry: Secondary publication
Title: A journey through the microscopic ages of DNA replication
Language: English
Date: 2022
Place of Publication: Darmstadt
Year of primary publication: 2016
Publisher: Springer
Journal or Publication Title: Protoplasma
Volume of the journal: 254
Issue Number: 3
DOI: 10.26083/tuprints-00013357
Corresponding Links:
Origin: Secondary publication

Scientific discoveries and technological advancements are inseparable but not always take place in a coherent chronological manner. In the next, we will provide a seemingly unconnected and serendipitous series of scientific facts that, in the whole, converged to unveil DNA and its duplication. We will not cover here the many and fundamental contributions from microbial genetics and in vitro biochemistry. Rather, in this journey, we will emphasize the interplay between microscopy development culminating on super resolution fluorescence microscopy (i.e., nanoscopy) and digital image analysis and its impact on our understanding of DNA duplication. We will interlace the journey with landmark concepts and experiments that have brought the cellular DNA replication field to its present state.

Status: Publisher's Version
URN: urn:nbn:de:tuda-tuprints-133579
Classification DDC: 500 Science and mathematics > 570 Life sciences, biology
600 Technology, medicine, applied sciences > 610 Medicine and health
Divisions: 10 Department of Biology > Cell Biology and Epigenetics
Date Deposited: 07 Mar 2022 13:38
Last Modified: 03 Mar 2023 09:45
URI: https://tuprints.ulb.tu-darmstadt.de/id/eprint/13357
PPN: 505407647
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