Summary: Changing Perspectives – From the Experimental to the Technological Turn in History and Philosophy of Science. In the 1960s the philosophy of science was transformed through the encounter with the history of science, resulting in a collaborative venture by the name of “History and Philosophy of Science” (HPS). Philosophy of science adopted ever more regularly the format of the case study to reconstruct certain episodes from the history of science, and historians were mostly interested in the production of scientific knowledge. The so-called “experimental turn” of the 1980s owed to this interaction between philosophy and history. Its guiding question remained quite traditional, however, namely “How do the sciences achieve an agreement between representation and reality?” Only the answers to this question broke with tradition by focusing not on theory but on the role of instruments and experiments. – Roughly 30 years after the experimental turn, another transformative encounter appears to be taking place. HPS is being transformed in the encounter with philosophy of technology. From the point of view of philosophy of technology, the question does not arise whether and how the agreement of mind and world, representation and reality can be achieved. When things are constructed, built or made, human thinking and physical materiality are inseparably intertwined. Instead of seeking to describe a mind-independent reality, technoscientific researchers are working to acquire and demonstrate capabilities of experimental or predictive control. When science is regarded as a kind of technology, a program of study opens up for epistemology and so do avenues for the historiography of science. History of science might now show how the problems and procedures of the sciences arise from and impinge back upon a world that is itself a product of science and technology. It thereby abandons its traditional HPS niche existence and joins forces with environmental history, history of technology, social, labor, and consumer history. Keywords: science and technoscience, history of the philosophy of science, philosophy of experiment, philosophy of technology, historiography of science, Ian Hacking, Schlüsselwörter: Wissenschaft und Technowissenschaft, Geschichte der Wissenschaftstheorie, Philosophie des Experiments, Technikphilosophie, Wissenschaftsgeschichte, Ian Hacking