Abstract Large Eddy Simulation in internal combustion Engine Dipl.-Ing Matteo Ghel� The internal combustion (IC) engine simulation is nowadays one of the most difficult proceeding during engine development. Simultaneously this is one of the most important phase because it leads to better acknowledgment of in-cylinder phenomena and suggests new method of emission reduction and control.\\ Large Eddy Simulation (LES) can help this process because of its instationary nature, in perfect agreement with motion, injection and combustion, typical instationary components in this kind of study.\\ This work focuses on a method which includes all the phenomena happening during IC engine cycle in a LES. \\ The main purpose of this work is to include combustion on the simulation obtaining a complete engine cycle. The work concentrates in particular on models development and investigation of the perfect computational domain movement, necessary to reach an optimal resolution during all the engine cycle phases. \\