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There is a continuing demand in machine tools for an increase in productivity. This can be achieved by higher speeds and process parameters, which demand structures with a high stiffness to weight ratio including the use of materials with a high specific modulus. The lack of standardized interfaces and more complex design and manufacturing process prevent the broad use of these materials. This applies especially for CFRP (carbon fiber reinforced polymer) which has the highest specific modulus compared to conventional construction materials. Due to that and the higher material damping in comparison with steel, parts out of CFRP can improve the precision of machine tools. These advantages often remain unutilized because of the challenging integration of CFRP parts. Therefore, this paper presents an innovative approach to use CFRP in a hybrid design for machine tool structures focusing on improved dynamic behavior, increased specific stiffness, and ease of manufacture.