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Spherical polyelectrolyte nanogels as templates to prepare hollow silica nanocarriers: observation by small angle X-ray scattering and TEM

Han, Haoya ; Li, Li ; Tian, Yuchuan ; Wang, Yunwei ; Ye, Zhishuang ; Yang, Qingsong ; Wang, Yiming ; Klitzing, Regine von ; Guo, Xuhong (2021):
Spherical polyelectrolyte nanogels as templates to prepare hollow silica nanocarriers: observation by small angle X-ray scattering and TEM. (Publisher's Version)
In: RSC Advances, 7 (76), pp. 47877-47885. Royal Society of Chemistry, ISSN 2046-2069,
DOI: 10.26083/tuprints-00019059,
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Item Type: Article
Origin: Secondary publication service
Status: Publisher's Version
Title: Spherical polyelectrolyte nanogels as templates to prepare hollow silica nanocarriers: observation by small angle X-ray scattering and TEM
Language: English
Abstract:

Hollow silica nanoparticles were prepared through generating a silica layer in spherical polyelectrolyte nanogels (SPN), which consisted of a solid core of polystyrene (PS) and a shell of crosslinked poly(acrylic acid) (PAA), followed by removing the PS core via solvent dissolution. Small angle X-ray scattering (SAXS) in combination with TEM were employed to observe SPN, silica–polymer composite, and hollow silica nanoparticles. It was confirmed that SAXS is a powerful method to monitor the generation of silica layer in SPN. The density and thickness of generated silica layer in SPN were found to be tunable by controlling the crosslinking density of the templates. The porous structure and pH sensitivity of silica layer allowed the obtained hollow silica to be ideal carriers for controlled drug delivery.

Journal or Publication Title: RSC Advances
Journal volume: 7
Number: 76
Publisher: Royal Society of Chemistry
Classification DDC: 500 Naturwissenschaften und Mathematik > 530 Physik
500 Naturwissenschaften und Mathematik > 540 Chemie
Divisions: Profile Areas > Thermo-Fluids & Interfaces
05 Department of Physics > Institute for Condensed Matter Physics
Date Deposited: 06 Sep 2021 12:23
Last Modified: 06 Sep 2021 12:24
DOI: 10.26083/tuprints-00019059
Corresponding Links:
URN: urn:nbn:de:tuda-tuprints-190597
URI: https://tuprints.ulb.tu-darmstadt.de/id/eprint/19059
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