Saul, Meike J. ; Emmerich, Anne C. ; Steinhilber, Dieter ; Suess, Beatrix (2019):
Regulation of Eicosanoid Pathways by MicroRNAs.
In: Frontiers in Pharmacology, 10, Frontiers, ISSN 1663-9812,
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Item Type: | Article |
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Origin: | Secondary publication via sponsored Golden Open Access |
Title: | Regulation of Eicosanoid Pathways by MicroRNAs |
Language: | English |
Abstract: | Over the last years, many microRNAs (miRNAs) have been identified that regulate the formation of bioactive lipid mediators such as prostanoids and leukotrienes. Many of these miRNAs are involved in complex regulatory circuits necessary for the finetuning of biological functions including inflammatory processes or cell growth. A better understanding of these networks will contribute to the development of novel therapeutic strategies for the treatment of inflammatory diseases and cancer. In this review, we provide an overview of the current knowledge of miRNA regulation in eicosanoid pathways with special focus on novel miRNA functions and regulatory circuits of leukotriene and prostaglandin biosynthesis. |
Journal or Publication Title: | Frontiers in Pharmacology |
Volume of the journal: | 10 |
Place of Publication: | Darmstadt |
Publisher: | Frontiers |
Classification DDC: | 500 Naturwissenschaften und Mathematik > 570 Biowissenschaften, Biologie |
Divisions: | 10 Department of Biology > Synthetic Genetic Circuits |
Date Deposited: | 30 Oct 2019 10:30 |
Last Modified: | 13 Dec 2022 10:25 |
Corresponding Links: | |
URN: | urn:nbn:de:tuda-tuprints-92305 |
URI: | https://tuprints.ulb.tu-darmstadt.de/id/eprint/9230 |
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