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Numerical Optimization of an Open-Ended Coaxial Slot Applicator for the Detection and Microwave Ablation of Tumors

Hessinger, Carolin ; Schüßler, Martin ; Klos, Sabrina ; Kochanek, Markus ; Jakoby, Rolf (2022):
Numerical Optimization of an Open-Ended Coaxial Slot Applicator for the Detection and Microwave Ablation of Tumors. (Publisher's Version)
In: Biology, 10 (9), MDPI, e-ISSN 2079-7737,
DOI: 10.26083/tuprints-00019981,
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Item Type: Article
Origin: Secondary publication DeepGreen
Status: Publisher's Version
Title: Numerical Optimization of an Open-Ended Coaxial Slot Applicator for the Detection and Microwave Ablation of Tumors
Language: English
Abstract:

A multiobjective optimization method for a dual-mode microwave applicator is proposed. Dual-modality means that microwaves are used apart from the treatment, and also for the monitoring of the microwave ablation intervention. (1) The use of computational models to develop and improve microwave ablation applicator geometries is essential for further advances in this field. (2) Numerical electromagnetic–thermal coupled simulation models are used to analyze the performance of the dual-mode applicator in liver tissue; the sensitivity evaluation of the dual-mode applicator’s sensing mode constrains the set of optimal solutions. (3) Three Pareto-optimal design parameter sets are derived that are optimal in terms of applicator efficiency as well as volume and sphericity of the ablation zone. The resulting designs of the dual-mode applicator provide a suitable sensitivity to distinguish between healthy and tumorous liver tissue. (4) The optimized designs are presented and numerically characterized. An improvement on the performance of previously proposed dual-mode applicator designs is achieved. The multiphysical simulation model of electromagnetic and thermal properties of the applicator is applicable for future comprehensive design procedures.

Alternative Abstract:
Alternative AbstractLanguage

Simple Summary: In this work, a parametric analysis of a dual-mode applicator for microwave ablation treatments is proposed to optimize the geometric parameters of the structure. The dual-mode concept means that the applicator comprises an additional sensing mode to determine the dielectric properties of the surrounding tissue before and during the ablation procedure. Based on numerical electromagnetic-thermal coupled simulations the most optimal design in terms of applicator efficiency as well as ablation zone volume and shape is determined that further fulfills the sensitivity requirements of the sensing mode. The multiobjective optimization problem is solved graphically with the so-called Pareto-optimization method. The resulting Pareto-optimal dual-mode applicator designs are characterized by electromagnetic and thermal simulations and discussed.

English
Journal or Publication Title: Biology
Volume of the journal: 10
Issue Number: 9
Publisher: MDPI
Collation: 12 Seiten
Uncontrolled Keywords: microwave ablation, microwave applicator, multiobjective optimization
Classification DDC: 500 Naturwissenschaften und Mathematik > 570 Biowissenschaften, Biologie
600 Technik, Medizin, angewandte Wissenschaften > 620 Ingenieurwissenschaften
Divisions: 18 Department of Electrical Engineering and Information Technology > Institute for Microwave Engineering and Photonics (IMP)
18 Department of Electrical Engineering and Information Technology > Institute for Telecommunications > Communications Engineering
Date Deposited: 02 May 2022 11:51
Last Modified: 02 May 2022 11:51
DOI: 10.26083/tuprints-00019981
Corresponding Links:
URN: urn:nbn:de:tuda-tuprints-199810
SWORD Depositor: Deep Green
URI: https://tuprints.ulb.tu-darmstadt.de/id/eprint/19981
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