Hessinger, Carolin ; Schüßler, Martin ; Klos, Sabrina ; Kochanek, Markus ; Jakoby, Rolf (2022):
Numerical Optimization of an Open-Ended Coaxial Slot Applicator for the Detection and Microwave Ablation of Tumors. (Publisher's Version)
In: Biology, 10 (9), MDPI, e-ISSN 2079-7737,
DOI: 10.26083/tuprints-00019981,
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Item Type: | Article | ||||
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Origin: | Secondary publication DeepGreen | ||||
Status: | Publisher's Version | ||||
Title: | Numerical Optimization of an Open-Ended Coaxial Slot Applicator for the Detection and Microwave Ablation of Tumors | ||||
Language: | English | ||||
Abstract: | A multiobjective optimization method for a dual-mode microwave applicator is proposed. Dual-modality means that microwaves are used apart from the treatment, and also for the monitoring of the microwave ablation intervention. (1) The use of computational models to develop and improve microwave ablation applicator geometries is essential for further advances in this field. (2) Numerical electromagnetic–thermal coupled simulation models are used to analyze the performance of the dual-mode applicator in liver tissue; the sensitivity evaluation of the dual-mode applicator’s sensing mode constrains the set of optimal solutions. (3) Three Pareto-optimal design parameter sets are derived that are optimal in terms of applicator efficiency as well as volume and sphericity of the ablation zone. The resulting designs of the dual-mode applicator provide a suitable sensitivity to distinguish between healthy and tumorous liver tissue. (4) The optimized designs are presented and numerically characterized. An improvement on the performance of previously proposed dual-mode applicator designs is achieved. The multiphysical simulation model of electromagnetic and thermal properties of the applicator is applicable for future comprehensive design procedures. |
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Journal or Publication Title: | Biology | ||||
Volume of the journal: | 10 | ||||
Issue Number: | 9 | ||||
Place of Publication: | Darmstadt | ||||
Publisher: | MDPI | ||||
Collation: | 12 Seiten | ||||
Uncontrolled Keywords: | microwave ablation, microwave applicator, multiobjective optimization | ||||
Classification DDC: | 500 Naturwissenschaften und Mathematik > 570 Biowissenschaften, Biologie 600 Technik, Medizin, angewandte Wissenschaften > 620 Ingenieurwissenschaften |
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Divisions: | 18 Department of Electrical Engineering and Information Technology > Institute for Microwave Engineering and Photonics (IMP) > Microwave Engineering 18 Department of Electrical Engineering and Information Technology > Institute for Telecommunications > Communications Engineering |
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Date Deposited: | 02 May 2022 11:51 | ||||
Last Modified: | 06 Oct 2022 11:52 | ||||
DOI: | 10.26083/tuprints-00019981 | ||||
Corresponding Links: | |||||
URN: | urn:nbn:de:tuda-tuprints-199810 | ||||
SWORD Depositor: | Deep Green | ||||
URI: | https://tuprints.ulb.tu-darmstadt.de/id/eprint/19981 | ||||
PPN: | 49985098X | ||||
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