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Regulation of Eicosanoid Pathways by MicroRNAs

Saul, Meike J. and Emmerich, Anne C. and Steinhilber, Dieter and Suess, Beatrix (2019):
Regulation of Eicosanoid Pathways by MicroRNAs.
10, In: Frontiers in Pharmacology, Frontiers, ISSN 1663-9812,
DOI: 10.3389/fphar.2019.00824,
Secondary publishing via sponsored Golden Open Access, [Article]

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Item Type: Article
Origin: Secondary publishing via sponsored Golden Open Access
Title: Regulation of Eicosanoid Pathways by MicroRNAs
Language: English
Abstract:

Over the last years, many microRNAs (miRNAs) have been identified that regulate the formation of bioactive lipid mediators such as prostanoids and leukotrienes. Many of these miRNAs are involved in complex regulatory circuits necessary for the finetuning of biological functions including inflammatory processes or cell growth. A better understanding of these networks will contribute to the development of novel therapeutic strategies for the treatment of inflammatory diseases and cancer. In this review, we provide an overview of the current knowledge of miRNA regulation in eicosanoid pathways with special focus on novel miRNA functions and regulatory circuits of leukotriene and prostaglandin biosynthesis.

Journal or Publication Title: Frontiers in Pharmacology
Volume: 10
Publisher: Frontiers
Classification DDC: 500 Naturwissenschaften und Mathematik > 570 Biowissenschaften, Biologie
Divisions: 10 Department of Biology > Synthetic Genetic Circuits
Date Deposited: 30 Oct 2019 10:30
Last Modified: 09 Jul 2020 02:48
DOI: 10.3389/fphar.2019.00824
URN: urn:nbn:de:tuda-tuprints-92305
URI: https://tuprints.ulb.tu-darmstadt.de/id/eprint/9230
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