TU Darmstadt / ULB / TUprints

MeCP2 and Chromatin Compartmentalization

Schmidt, Annika and Zhang, Hui and Cardoso, M. Cristina (2020):
MeCP2 and Chromatin Compartmentalization.
In: Cells, 9, (4), MDPI, ISSN 2073-4409,
DOI: 10.25534/tuprints-00013360,
[Online-Edition: https://doi.org/10.3390/cells9040878],
Secondary publishing via sponsored Golden Open Access, [Article]

[img]
Preview
Text
cells-09-00878-v2.pdf
Available under CC-BY 4.0 International - Creative Commons, Attribution.

Download (1MB) | Preview
Item Type: Article
Origin: Secondary publishing via sponsored Golden Open Access
Title: MeCP2 and Chromatin Compartmentalization
Language: English
Abstract:

Methyl-CpG binding protein 2 (MeCP2) is a multifunctional epigenetic reader playing a role in transcriptional regulation and chromatin structure, which was linked to Rett syndrome in humans. Here, we focus on its isoforms and functional domains, interactions, modifications and mutations found in Rett patients. Finally, we address how these properties regulate and mediate the ability of MeCP2 to orchestrate chromatin compartmentalization and higher order genome architecture.

Journal or Publication Title: Cells
Journal volume: 9
Number: 4
Publisher: MDPI
Classification DDC: 500 Naturwissenschaften und Mathematik > 570 Biowissenschaften, Biologie
Divisions: 10 Department of Biology > Cell Biology and Epigenetics
Date Deposited: 25 Aug 2020 09:22
Last Modified: 25 Aug 2020 09:54
DOI: 10.25534/tuprints-00013360
Official URL: https://doi.org/10.3390/cells9040878
URN: urn:nbn:de:tuda-tuprints-133604
URI: https://tuprints.ulb.tu-darmstadt.de/id/eprint/13360
Export:
Actions (login required)
View Item View Item